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Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair.
Avolio E, Meloni M, Spencer HL, Riu F, Katare R, Mangialardi G, Oikawa A, Rodriguez-Arabaolaza I, Dang Z, Mitchell K, Reni C, Alvino VV, Rowlinson J, Livi U, Cesselli D, Angelini G, Emanueli C, Beltrami AP, Madeddu P. Avolio E, et al. Among authors: spencer hl. Circ Res. 2015 May 8;116(10):e81-94. doi: 10.1161/CIRCRESAHA.115.306146. Epub 2015 Mar 23. Circ Res. 2015. PMID: 25801898 Free article.
Transplantation of Allogeneic Pericytes Improves Myocardial Vascularization and Reduces Interstitial Fibrosis in a Swine Model of Reperfused Acute Myocardial Infarction.
Alvino VV, Fernández-Jiménez R, Rodriguez-Arabaolaza I, Slater S, Mangialardi G, Avolio E, Spencer H, Culliford L, Hassan S, Sueiro Ballesteros L, Herman A, Ayaon-Albarrán A, Galán-Arriola C, Sánchez-González J, Hennessey H, Delmege C, Ascione R, Emanueli C, Angelini GD, Ibanez B, Madeddu P. Alvino VV, et al. J Am Heart Assoc. 2018 Jan 22;7(2):e006727. doi: 10.1161/JAHA.117.006727. J Am Heart Assoc. 2018. PMID: 29358198 Free PMC article.
Expansion and characterization of neonatal cardiac pericytes provides a novel cellular option for tissue engineering in congenital heart disease.
Avolio E, Rodriguez-Arabaolaza I, Spencer HL, Riu F, Mangialardi G, Slater SC, Rowlinson J, Alvino VV, Idowu OO, Soyombo S, Oikawa A, Swim MM, Kong CH, Cheng H, Jia H, Ghorbel MT, Hancox JC, Orchard CH, Angelini G, Emanueli C, Caputo M, Madeddu P. Avolio E, et al. Among authors: spencer hl. J Am Heart Assoc. 2015 Jun 16;4(6):e002043. doi: 10.1161/JAHA.115.002043. J Am Heart Assoc. 2015. PMID: 26080813 Free PMC article.
Derivation of endothelial cells from human embryonic stem cells by directed differentiation: analysis of microRNA and angiogenesis in vitro and in vivo.
Kane NM, Meloni M, Spencer HL, Craig MA, Strehl R, Milligan G, Houslay MD, Mountford JC, Emanueli C, Baker AH. Kane NM, et al. Among authors: spencer hl. Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1389-97. doi: 10.1161/ATVBAHA.110.204800. Epub 2010 Apr 29. Arterioscler Thromb Vasc Biol. 2010. PMID: 20431067
Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia.
Gubernator M, Slater SC, Spencer HL, Spiteri I, Sottoriva A, Riu F, Rowlinson J, Avolio E, Katare R, Mangialardi G, Oikawa A, Reni C, Campagnolo P, Spinetti G, Touloumis A, Tavaré S, Prandi F, Pesce M, Hofner M, Klemens V, Emanueli C, Angelini G, Madeddu P. Gubernator M, et al. Among authors: spencer hl. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):675-88. doi: 10.1161/ATVBAHA.114.304989. Epub 2015 Jan 8. Arterioscler Thromb Vasc Biol. 2015. PMID: 25573856
Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction.
Ascione R, Rowlinson J, Avolio E, Katare R, Meloni M, Spencer HL, Mangialardi G, Norris C, Kränkel N, Spinetti G, Emanueli C, Madeddu P. Ascione R, et al. Among authors: spencer hl. Stem Cell Res Ther. 2015 Apr 11;6(1):53. doi: 10.1186/s13287-015-0028-y. Stem Cell Res Ther. 2015. PMID: 25889213 Free PMC article.
Role of TPBG (Trophoblast Glycoprotein) Antigen in Human Pericyte Migratory and Angiogenic Activity.
Spencer HL, Jover E, Cathery W, Avolio E, Rodriguez-Arabaolaza I, Thomas AC, Alvino VV, Sala-Newby G, Dang Z, Fagnano M, Reni C, Rowlinson J, Vono R, Spinetti G, Beltrami AP, Gargioli C, Caporali A, Angelini G, Madeddu P. Spencer HL, et al. Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1113-1124. doi: 10.1161/ATVBAHA.119.312665. Arterioscler Thromb Vasc Biol. 2019. PMID: 31018661 Free article.
Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product.
MacAskill MG, Saif J, Condie A, Jansen MA, MacGillivray TJ, Tavares AAS, Fleisinger L, Spencer HL, Besnier M, Martin E, Biglino G, Newby DE, Hadoke PWF, Mountford JC, Emanueli C, Baker AH. MacAskill MG, et al. Among authors: spencer hl. Mol Ther. 2018 Jul 5;26(7):1669-1684. doi: 10.1016/j.ymthe.2018.03.017. Epub 2018 Mar 28. Mol Ther. 2018. PMID: 29703701 Free PMC article.
43 results