Lopiccolo J - Search Results

1

Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5.

Salamon RS, Dbouk HA, Collado D, Lopiccolo J, Bresnick AR, Backer JM. Salamon RS, et al. Among authors: lopiccolo j. Methods Mol Biol. 2015;1298:271-81. doi: 10.1007/978-1-4939-2569-8_23. Methods Mol Biol. 2015. PMID: 25800850 Free PMC article.

2

Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.

LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. LoPiccolo J, et al. J Biol Chem. 2015 Dec 18;290(51):30390-405. doi: 10.1074/jbc.M115.689604. Epub 2015 Oct 16. J Biol Chem. 2015. PMID: 26475863 Free PMC article.

3

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM. Erami Z, et al. Among authors: lopiccolo j. Biochem J. 2017 Nov 16;474(23):3903-3914. doi: 10.1042/BCJ20170279. Biochem J. 2017. PMID: 29046393 Free PMC article.

4

Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.

Shymanets A, Prajwal, Vadas O, Czupalla C, LoPiccolo J, Brenowitz M, Ghigo A, Hirsch E, Krause E, Wetzker R, Williams RL, Harteneck C, Nürnberg B. Shymanets A, et al. Among authors: lopiccolo j. Biochem J. 2015 Jul 1;469(1):59-69. doi: 10.1042/BJ20150099. Biochem J. 2015. PMID: 26173259 Free PMC article.

5

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations.

LoPiccolo J, Blumenthal GM, Bernstein WB, Dennis PA. LoPiccolo J, et al. Drug Resist Updat. 2008 Feb-Apr;11(1-2):32-50. doi: 10.1016/j.drup.2007.11.003. Epub 2007 Dec 31. Drug Resist Updat. 2008. PMID: 18166498 Free PMC article. Review.

6

Targeting Akt in cancer therapy.

LoPiccolo J, Granville CA, Gills JJ, Dennis PA. LoPiccolo J, et al. Anticancer Drugs. 2007 Sep;18(8):861-74. doi: 10.1097/CAD.0b013e3280cc2c6f. Anticancer Drugs. 2007. PMID: 17667591 Review.

7

Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.

Gills JJ, Lopiccolo J, Dennis PA. Gills JJ, et al. Among authors: lopiccolo j. Autophagy. 2008 Jan;4(1):107-9. doi: 10.4161/auto.5224. Epub 2007 Oct 31. Autophagy. 2008. PMID: 18000394

8

Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine.

Gills JJ, Zhang C, Abu-Asab MS, Castillo SS, Marceau C, LoPiccolo J, Kozikowski AP, Tsokos M, Goldkorn T, Dennis PA. Gills JJ, et al. Among authors: lopiccolo j. Cell Death Dis. 2012 Jul 5;3(7):e340. doi: 10.1038/cddis.2012.72. Cell Death Dis. 2012. PMID: 22764099 Free PMC article.

9

Prognostic significance of clinical factors and Akt activation in patients with bronchioloalveolar carcinoma.

Tsurutani J, Steinberg SM, Ballas M, Robertson M, LoPiccolo J, Soda H, Kohno S, Egilsson V, Dennis PA. Tsurutani J, et al. Among authors: lopiccolo j. Lung Cancer. 2007 Jan;55(1):115-21. doi: 10.1016/j.lungcan.2006.09.026. Epub 2006 Nov 13. Lung Cancer. 2007. PMID: 17097759 Free PMC article.

10

PTEN hamartomatous tumor syndromes (PHTS): rare syndromes with great relevance to common cancers and targeted drug development.

Lopiccolo J, Ballas MS, Dennis PA. Lopiccolo J, et al. Crit Rev Oncol Hematol. 2007 Sep;63(3):203-14. doi: 10.1016/j.critrevonc.2007.06.002. Epub 2007 Jul 20. Crit Rev Oncol Hematol. 2007. PMID: 17643312 Review.

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