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Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.
J Neurosci. 2015 Mar 18;35(11):4599-613. doi: 10.1523/JNEUROSCI.4764-13.2015.
J Neurosci. 2015.
PMID: 25788677
Free PMC article.
Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants.
Wifling D, Löffel K, Nordemann U, Strasser A, Bernhardt G, Dove S, Seifert R, Buschauer A.
Wifling D, et al. Among authors: nordemann u.
Br J Pharmacol. 2015 Feb;172(3):785-98. doi: 10.1111/bph.12801. Epub 2014 Sep 5.
Br J Pharmacol. 2015.
PMID: 24903527
Free PMC article.
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Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts.
Nordemann U, Wifling D, Schnell D, Bernhardt G, Stark H, Seifert R, Buschauer A.
Nordemann U, et al.
PLoS One. 2013 Sep 2;8(9):e73961. doi: 10.1371/journal.pone.0073961. eCollection 2013.
PLoS One. 2013.
PMID: 24023919
Free PMC article.
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Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.
Geyer R, Nordemann U, Strasser A, Wittmann HJ, Buschauer A.
Geyer R, et al. Among authors: nordemann u.
J Med Chem. 2016 Apr 14;59(7):3452-70. doi: 10.1021/acs.jmedchem.6b00120. Epub 2016 Apr 5.
J Med Chem. 2016.
PMID: 27007611
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