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Metabolite mapping reveals severe widespread perturbation of multiple metabolic processes in Huntington's disease human brain.
Patassini S, Begley P, Xu J, Church SJ, Reid SJ, Kim EH, Curtis MA, Dragunow M, Waldvogel HJ, Snell RG, Unwin RD, Faull RL, Cooper GJ. Patassini S, et al. Among authors: begley p. Biochim Biophys Acta. 2016 Sep;1862(9):1650-62. doi: 10.1016/j.bbadis.2016.06.002. Epub 2016 Jun 4. Biochim Biophys Acta. 2016. PMID: 27267344 Free article.
Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder.
Xu J, Begley P, Church SJ, Patassini S, Hollywood KA, Jüllig M, Curtis MA, Waldvogel HJ, Faull RL, Unwin RD, Cooper GJ. Xu J, et al. Among authors: begley p. Biochim Biophys Acta. 2016 Jun;1862(6):1084-92. doi: 10.1016/j.bbadis.2016.03.001. Epub 2016 Mar 5. Biochim Biophys Acta. 2016. PMID: 26957286 Free PMC article.
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry.
Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, Brown M, Knowles JD, Halsall A, Haselden JN, Nicholls AW, Wilson ID, Kell DB, Goodacre R; Human Serum Metabolome (HUSERMET) Consortium. Dunn WB, et al. Among authors: begley p. Nat Protoc. 2011 Jun 30;6(7):1060-83. doi: 10.1038/nprot.2011.335. Nat Protoc. 2011. PMID: 21720319
Molecular phenotyping of a UK population: defining the human serum metabolome.
Dunn WB, Lin W, Broadhurst D, Begley P, Brown M, Zelena E, Vaughan AA, Halsall A, Harding N, Knowles JD, Francis-McIntyre S, Tseng A, Ellis DI, O'Hagan S, Aarons G, Benjamin B, Chew-Graham S, Moseley C, Potter P, Winder CL, Potts C, Thornton P, McWhirter C, Zubair M, Pan M, Burns A, Cruickshank JK, Jayson GC, Purandare N, Wu FC, Finn JD, Haselden JN, Nicholls AW, Wilson ID, Goodacre R, Kell DB. Dunn WB, et al. Among authors: begley p. Metabolomics. 2015;11(1):9-26. doi: 10.1007/s11306-014-0707-1. Epub 2014 Jul 25. Metabolomics. 2015. PMID: 25598764 Free PMC article.
41 results