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Activation of p38 mitogen-activated protein kinase is critical step for acquisition of effector function in cytokine-activated T cells, but acts as a negative regulator in T cells activated through the T-cell receptor.
Li C, Beavis P, Palfreeman AC, Amjadi P, Kennedy A, Brennan FM. Li C, et al. Among authors: amjadi p. Immunology. 2011 Jan;132(1):104-10. doi: 10.1111/j.1365-2567.2010.03345.x. Epub 2010 Sep 28. Immunology. 2011. PMID: 20875074 Free PMC article.
Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.
Andersson AK, Sumariwalla PF, McCann FE, Amjadi P, Chang C, McNamee K, Tornehave D, Haase C, Agersø H, Stennicke VW, Ahern D, Ursø B, Trowsdale J, Feldmann M, Brennan FM. Andersson AK, et al. Among authors: amjadi p. Arthritis Rheum. 2011 Sep;63(9):2617-29. doi: 10.1002/art.30460. Arthritis Rheum. 2011. PMID: 21618462 Free article.
Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells.
Beavis PA, Gregory B, Green P, Cribbs AP, Kennedy A, Amjadi P, Palfreeman AC, Feldmann M, Brennan FM. Beavis PA, et al. Among authors: amjadi p. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16717-22. doi: 10.1073/pnas.1112722108. Epub 2011 Sep 16. Proc Natl Acad Sci U S A. 2011. PMID: 21926327 Free PMC article.
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