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α-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration.
Boggs AE, Vitolo MI, Whipple RA, Charpentier MS, Goloubeva OG, Ioffe OB, Tuttle KC, Slovic J, Lu Y, Mills GB, Martin SS. Boggs AE, et al. Among authors: charpentier ms. Cancer Res. 2015 Jan 1;75(1):203-15. doi: 10.1158/0008-5472.CAN-13-3563. Epub 2014 Dec 12. Cancer Res. 2015. PMID: 25503560 Free PMC article.
The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence.
Thompson KN, Whipple RA, Yoon JR, Lipsky M, Charpentier MS, Boggs AE, Chakrabarti KR, Bhandary L, Hessler LK, Martin SS, Vitolo MI. Thompson KN, et al. Among authors: charpentier ms. Oncotarget. 2015 Nov 3;6(34):35231-46. doi: 10.18632/oncotarget.6159. Oncotarget. 2015. PMID: 26497685 Free PMC article.
18 results