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p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Cudejko C, Wouters K, Fuentes L, Hannou SA, Paquet C, Bantubungi K, Bouchaert E, Vanhoutte J, Fleury S, Remy P, Tailleux A, Chinetti-Gbaguidi G, Dombrowicz D, Staels B, Paumelle R. Cudejko C, et al. Among authors: hannou sa. Blood. 2011 Sep 1;118(9):2556-66. doi: 10.1182/blood-2010-10-313106. Epub 2011 Jun 2. Blood. 2011. PMID: 21636855 Free PMC article.
Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype.
Fuentes L, Wouters K, Hannou SA, Cudejko C, Rigamonti E, Mayi TH, Derudas B, Pattou F, Chinetti-Gbaguidi G, Staels B, Paumelle R. Fuentes L, et al. Among authors: hannou sa. Diabetologia. 2011 Dec;54(12):3150-6. doi: 10.1007/s00125-011-2324-0. Epub 2011 Oct 4. Diabetologia. 2011. PMID: 21968977 Free PMC article.
Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development.
Wouters K, Cudejko C, Gijbels MJ, Fuentes L, Bantubungi K, Vanhoutte J, Dièvart R, Paquet C, Bouchaert E, Hannou SA, Gizard F, Tailleux A, de Winther MP, Staels B, Paumelle R. Wouters K, et al. Among authors: hannou sa. PLoS One. 2012;7(3):e32440. doi: 10.1371/journal.pone.0032440. Epub 2012 Mar 5. PLoS One. 2012. PMID: 22403661 Free PMC article.
The tumour suppressor CDKN2A/p16INK4a regulates adipogenesis and bone marrow-dependent development of perivascular adipose tissue.
Wouters K, Deleye Y, Hannou SA, Vanhoutte J, Maréchal X, Coisne A, Tagzirt M, Derudas B, Bouchaert E, Duhem C, Vallez E, Schalkwijk CG, Pattou F, Montaigne D, Staels B, Paumelle R. Wouters K, et al. Among authors: hannou sa. Diab Vasc Dis Res. 2017 Nov;14(6):516-524. doi: 10.1177/1479164117728012. Epub 2017 Sep 2. Diab Vasc Dis Res. 2017. PMID: 28868898 Free PMC article.
Cdkn2a deficiency promotes adipose tissue browning.
Rabhi N, Hannou SA, Gromada X, Salas E, Yao X, Oger F, Carney C, Lopez-Mejia IC, Durand E, Rabearivelo I, Bonnefond A, Caron E, Fajas L, Dani C, Froguel P, Annicotte JS. Rabhi N, et al. Among authors: hannou sa. Mol Metab. 2018 Feb;8:65-76. doi: 10.1016/j.molmet.2017.11.012. Epub 2017 Dec 1. Mol Metab. 2018. PMID: 29237539 Free PMC article.
Hepatic PPARα is critical in the metabolic adaptation to sepsis.
Paumelle R, Haas JT, Hennuyer N, Baugé E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B. Paumelle R, et al. Among authors: hannou sa. J Hepatol. 2019 May;70(5):963-973. doi: 10.1016/j.jhep.2018.12.037. Epub 2019 Jan 21. J Hepatol. 2019. PMID: 30677458 Free PMC article.
CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R. Deleye Y, et al. Among authors: hannou sa. J Biol Chem. 2020 Dec 11;295(50):17310-17322. doi: 10.1074/jbc.RA120.012543. Epub 2020 Oct 9. J Biol Chem. 2020. PMID: 33037071 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33453977
24 results