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FAAH genetic variation enhances fronto-amygdala function in mouse and human.
Dincheva I, Drysdale AT, Hartley CA, Johnson DC, Jing D, King EC, Ra S, Gray JM, Yang R, DeGruccio AM, Huang C, Cravatt BF, Glatt CE, Hill MN, Casey BJ, Lee FS. Dincheva I, et al. Among authors: cravatt bf. Nat Commun. 2015 Mar 3;6:6395. doi: 10.1038/ncomms7395. Nat Commun. 2015. PMID: 25731744 Free PMC article.
Structure-guided inhibitor design for human FAAH by interspecies active site conversion.
Mileni M, Johnson DS, Wang Z, Everdeen DS, Liimatta M, Pabst B, Bhattacharya K, Nugent RA, Kamtekar S, Cravatt BF, Ahn K, Stevens RC. Mileni M, et al. Among authors: cravatt bf. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12820-4. doi: 10.1073/pnas.0806121105. Epub 2008 Aug 27. Proc Natl Acad Sci U S A. 2008. PMID: 18753625 Free PMC article.
Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling.
Alpár A, Tortoriello G, Calvigioni D, Niphakis MJ, Milenkovic I, Bakker J, Cameron GA, Hanics J, Morris CV, Fuzik J, Kovacs GG, Cravatt BF, Parnavelas JG, Andrews WD, Hurd YL, Keimpema E, Harkany T. Alpár A, et al. Among authors: cravatt bf. Nat Commun. 2014 Jul 17;5:4421. doi: 10.1038/ncomms5421. Nat Commun. 2014. PMID: 25030704 Free PMC article.
580 results