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HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.
Sepulveda-Diaz JE, Alavi Naini SM, Huynh MB, Ouidja MO, Yanicostas C, Chantepie S, Villares J, Lamari F, Jospin E, van Kuppevelt TH, Mensah-Nyagan AG, Raisman-Vozari R, Soussi-Yanicostas N, Papy-Garcia D. Sepulveda-Diaz JE, et al. Among authors: chantepie s. Brain. 2015 May;138(Pt 5):1339-54. doi: 10.1093/brain/awv056. Epub 2015 Apr 4. Brain. 2015. PMID: 25842390 Free PMC article.
New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors.
Byrne DP, Li Y, Ramakrishnan K, Barsukov IL, Yates EA, Eyers CE, Papy-Garcia D, Chantepie S, Pagadala V, Liu J, Wells C, Drewry DH, Zuercher WJ, Berry NG, Fernig DG, Eyers PA. Byrne DP, et al. Among authors: chantepie s. Biochem J. 2018 Aug 14;475(15):2417-2433. doi: 10.1042/BCJ20180265. Biochem J. 2018. PMID: 29934491 Free PMC article.
3-O-sulfated heparan sulfate interactors target synaptic adhesion molecules from neonatal mouse brain and inhibit neural activity and synaptogenesis in vitro.
Maïza A, Sidahmed-Adrar N, Michel PP, Carpentier G, Habert D, Dalle C, Redouane W, Hamza M, van Kuppevelt TH, Ouidja MO, Courty J, Chantepie S, Papy-Garcia D, Stettler O. Maïza A, et al. Among authors: chantepie s. Sci Rep. 2020 Nov 5;10(1):19114. doi: 10.1038/s41598-020-76030-4. Sci Rep. 2020. PMID: 33154448 Free PMC article.
Heparan sulfate functions are altered in the osteoarthritic cartilage.
Shamdani S, Chantepie S, Flageollet C, Henni-Chebra N, Jouan Y, Eymard F, Hay E, Cohen-Solal M, Papy-Garcia D, Chevalier X, Albanese P. Shamdani S, et al. Among authors: chantepie s. Arthritis Res Ther. 2020 Dec 7;22(1):283. doi: 10.1186/s13075-020-02352-3. Arthritis Res Ther. 2020. PMID: 33287871 Free PMC article.
SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects.
Dubail J, Huber C, Chantepie S, Sonntag S, Tüysüz B, Mihci E, Gordon CT, Steichen-Gersdorf E, Amiel J, Nur B, Stolte-Dijkstra I, van Eerde AM, van Gassen KL, Breugem CC, Stegmann A, Lekszas C, Maroofian R, Karimiani EG, Bruneel A, Seta N, Munnich A, Papy-Garcia D, De La Dure-Molla M, Cormier-Daire V. Dubail J, et al. Among authors: chantepie s. Nat Commun. 2018 Aug 6;9(1):3087. doi: 10.1038/s41467-018-05191-8. Nat Commun. 2018. PMID: 30082715 Free PMC article.
A heparan sulfate-based matrix therapy reduces brain damage and enhances functional recovery following stroke.
Khelif Y, Toutain J, Quittet MS, Chantepie S, Laffray X, Valable S, Divoux D, Sineriz F, Pascolo-Rebouillat E, Papy-Garcia D, Barritault D, Touzani O, Bernaudin M. Khelif Y, et al. Among authors: chantepie s. Theranostics. 2018 Nov 12;8(21):5814-5827. doi: 10.7150/thno.28252. eCollection 2018. Theranostics. 2018. PMID: 30613264 Free PMC article.
144 results