Fox JH - Search Results

1

Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.

Berggren KL, Chen J, Fox J, Miller J, Dodds L, Dugas B, Vargas L, Lothian A, McAllum E, Volitakis I, Roberts B, Bush AI, Fox JH. Berggren KL, et al. Among authors: fox j, fox jh. Redox Biol. 2015;4:363-74. doi: 10.1016/j.redox.2015.02.002. Epub 2015 Feb 11. Redox Biol. 2015. PMID: 25703232 Free PMC article.

2

Iron accumulates in Huntington's disease neurons: protection by deferoxamine.

Chen J, Marks E, Lai B, Zhang Z, Duce JA, Lam LQ, Volitakis I, Bush AI, Hersch S, Fox JH. Chen J, et al. Among authors: fox jh. PLoS One. 2013 Oct 11;8(10):e77023. doi: 10.1371/journal.pone.0077023. eCollection 2013. PLoS One. 2013. PMID: 24146952 Free PMC article.

3

Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice.

Berggren KL, Lu Z, Fox JA, Dudenhoeffer M, Agrawal S, Fox JH. Berggren KL, et al. Among authors: fox ja, fox jh. J Huntingtons Dis. 2016;5(1):53-63. doi: 10.3233/JHD-150182. J Huntingtons Dis. 2016. PMID: 27079948 Free PMC article.

4

Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model.

Lu Z, Marks E, Chen J, Moline J, Barrows L, Raisbeck M, Volitakis I, Cherny RA, Chopra V, Bush AI, Hersch S, Fox JH. Lu Z, et al. Among authors: fox jh. Neurobiol Dis. 2014 Nov;71:34-42. doi: 10.1016/j.nbd.2014.06.022. Epub 2014 Jul 8. Neurobiol Dis. 2014. PMID: 25014023

5

Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review.

Agrawal S, Berggren KL, Marks E, Fox JH. Agrawal S, et al. Among authors: fox jh. Nutr Rev. 2017 Jun 1;75(6):456-470. doi: 10.1093/nutrit/nux015. Nutr Rev. 2017. PMID: 28505363 Free PMC article. Review.

6

Amyloid Precursor Protein Haploinsufficiency Preferentially Mediates Brain Iron Accumulation in Mice Transgenic for The Huntington's Disease Mutation.

Berggren K, Agrawal S, Fox JA, Hildenbrand J, Nelson R, Bush AI, Fox JH. Berggren K, et al. Among authors: fox ja, fox jh. J Huntingtons Dis. 2017;6(2):115-125. doi: 10.3233/JHD-170242. J Huntingtons Dis. 2017. PMID: 28550267 Free PMC article.

7

Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically.

Agrawal S, Fox J, Thyagarajan B, Fox JH. Agrawal S, et al. Among authors: fox j, fox jh. Free Radic Biol Med. 2018 May 20;120:317-329. doi: 10.1016/j.freeradbiomed.2018.04.002. Epub 2018 Apr 4. Free Radic Biol Med. 2018. PMID: 29625173 Free PMC article.

8

Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.

Fox JH, Connor T, Stiles M, Kama J, Lu Z, Dorsey K, Lieberman G, Sapp E, Cherny RA, Banks M, Volitakis I, DiFiglia M, Berezovska O, Bush AI, Hersch SM. Fox JH, et al. J Biol Chem. 2011 May 20;286(20):18320-30. doi: 10.1074/jbc.M110.199448. Epub 2011 Mar 30. J Biol Chem. 2011. PMID: 21454633 Free PMC article.

9

Mechanisms of copper ion mediated Huntington's disease progression.

Fox JH, Kama JA, Lieberman G, Chopra R, Dorsey K, Chopra V, Volitakis I, Cherny RA, Bush AI, Hersch S. Fox JH, et al. PLoS One. 2007 Mar 28;2(3):e334. doi: 10.1371/journal.pone.0000334. PLoS One. 2007. PMID: 17396163 Free PMC article.

10

Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease.

Agrawal S, Fox JH. Agrawal S, et al. Among authors: fox jh. Mitochondrion. 2019 Jul;47:318-329. doi: 10.1016/j.mito.2019.03.004. Epub 2019 Mar 20. Mitochondrion. 2019. PMID: 30902619 Free PMC article.

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