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Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery.
Pascucci L, Coccè V, Bonomi A, Ami D, Ceccarelli P, Ciusani E, Viganò L, Locatelli A, Sisto F, Doglia SM, Parati E, Bernardo ME, Muraca M, Alessandri G, Bondiolotti G, Pessina A. Pascucci L, et al. J Control Release. 2014 Oct 28;192:262-70. doi: 10.1016/j.jconrel.2014.07.042. Epub 2014 Jul 30. J Control Release. 2014. PMID: 25084218
Mesenchymal Stem Cell-Derived Extracellular Vesicles as Mediators of Anti-Inflammatory Effects: Endorsement of Macrophage Polarization.
Lo Sicco C, Reverberi D, Balbi C, Ulivi V, Principi E, Pascucci L, Becherini P, Bosco MC, Varesio L, Franzin C, Pozzobon M, Cancedda R, Tasso R. Lo Sicco C, et al. Among authors: pascucci l. Stem Cells Transl Med. 2017 Mar;6(3):1018-1028. doi: 10.1002/sctm.16-0363. Epub 2017 Jan 31. Stem Cells Transl Med. 2017. PMID: 28186708 Free PMC article.
First Characterization of Human Amniotic Fluid Stem Cell Extracellular Vesicles as a Powerful Paracrine Tool Endowed with Regenerative Potential.
Balbi C, Piccoli M, Barile L, Papait A, Armirotti A, Principi E, Reverberi D, Pascucci L, Becherini P, Varesio L, Mogni M, Coviello D, Bandiera T, Pozzobon M, Cancedda R, Bollini S. Balbi C, et al. Among authors: pascucci l. Stem Cells Transl Med. 2017 May;6(5):1340-1355. doi: 10.1002/sctm.16-0297. Epub 2017 Mar 8. Stem Cells Transl Med. 2017. PMID: 28271621 Free PMC article.
Mesenchymal stem/stromal cell extracellular vesicles: From active principle to next generation drug delivery system.
Crivelli B, Chlapanidas T, Perteghella S, Lucarelli E, Pascucci L, Brini AT, Ferrero I, Marazzi M, Pessina A, Torre ML; Italian Mesenchymal Stem Cell Group (GISM). Crivelli B, et al. Among authors: pascucci l. J Control Release. 2017 Sep 28;262:104-117. doi: 10.1016/j.jconrel.2017.07.023. Epub 2017 Jul 20. J Control Release. 2017. PMID: 28736264 Review.
Characterization of Extracellular Vesicles in Osteoporotic Patients Compared to Osteopenic and Healthy Controls.
Pepe J, Rossi M, Battafarano G, Vernocchi P, Conte F, Marzano V, Mariani E, Mortera SL, Cipriani C, Rana I, Buonuomo PS, Bartuli A, De Martino V, Pelle S, Pascucci L, Toniolo RM, Putignani L, Minisola S, Del Fattore A. Pepe J, et al. Among authors: pascucci l. J Bone Miner Res. 2022 Nov;37(11):2186-2200. doi: 10.1002/jbmr.4688. Epub 2022 Sep 14. J Bone Miner Res. 2022. PMID: 36053959 Free PMC article.
Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts.
Pacioni S, D'Alessandris QG, Giannetti S, Morgante L, Coccè V, Bonomi A, Buccarelli M, Pascucci L, Alessandri G, Pessina A, Ricci-Vitiani L, Falchetti ML, Pallini R. Pacioni S, et al. Among authors: pascucci l. Stem Cell Res Ther. 2017 Mar 9;8(1):53. doi: 10.1186/s13287-017-0516-3. Stem Cell Res Ther. 2017. PMID: 28279193 Free PMC article.
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