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Page 1
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis.
McCluskey A, Daniel JA, Hadzic G, Chau N, Clayton EL, Mariana A, Whiting A, Gorgani NN, Lloyd J, Quan A, Moshkanbaryans L, Krishnan S, Perera S, Chircop M, von Kleist L, McGeachie AB, Howes MT, Parton RG, Campbell M, Sakoff JA, Wang X, Sun JY, Robertson MJ, Deane FM, Nguyen TH, Meunier FA, Cousin MA, Robinson PJ. McCluskey A, et al. Among authors: von kleist l. Traffic. 2013 Dec;14(12):1272-89. doi: 10.1111/tra.12119. Epub 2013 Oct 9. Traffic. 2013. PMID: 24025110 Free PMC article.
Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.
von Kleist L, Stahlschmidt W, Bulut H, Gromova K, Puchkov D, Robertson MJ, MacGregor KA, Tomilin N, Pechstein A, Chau N, Chircop M, Sakoff J, von Kries JP, Saenger W, Kräusslich HG, Shupliakov O, Robinson PJ, McCluskey A, Haucke V. von Kleist L, et al. Among authors: von kries jp. Cell. 2011 Aug 5;146(3):471-84. doi: 10.1016/j.cell.2011.06.025. Cell. 2011. PMID: 21816279 Free article.
Development of 1,8-naphthalimides as clathrin inhibitors.
MacGregor KA, Robertson MJ, Young KA, von Kleist L, Stahlschmidt W, Whiting A, Chau N, Robinson PJ, Haucke V, McCluskey A. MacGregor KA, et al. Among authors: von kleist l. J Med Chem. 2014 Jan 9;57(1):131-43. doi: 10.1021/jm4015263. Epub 2013 Dec 18. J Med Chem. 2014. PMID: 24299503
The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity.
Robertson MJ, Hadzic G, Ambrus J, Pomè DY, Hyde E, Whiting A, Mariana A, von Kleist L, Chau N, Haucke V, Robinson PJ, McCluskey A. Robertson MJ, et al. Among authors: von kleist l. ACS Med Chem Lett. 2012 Mar 26;3(5):352-6. doi: 10.1021/ml200284s. eCollection 2012 May 10. ACS Med Chem Lett. 2012. PMID: 24900478 Free PMC article.
Synthesis of the Pitstop family of clathrin inhibitors.
Robertson MJ, Deane FM, Stahlschmidt W, von Kleist L, Haucke V, Robinson PJ, McCluskey A. Robertson MJ, et al. Among authors: von kleist l. Nat Protoc. 2014 Jul;9(7):1592-606. doi: 10.1038/nprot.2014.106. Epub 2014 Jun 12. Nat Protoc. 2014. PMID: 24922269
5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors.
Robertson MJ, Horatscheck A, Sauer S, von Kleist L, Baker JR, Stahlschmidt W, Nazaré M, Whiting A, Chau N, Robinson PJ, Haucke V, McCluskey A. Robertson MJ, et al. Among authors: von kleist l. Org Biomol Chem. 2016 Nov 29;14(47):11266-11278. doi: 10.1039/c6ob02308h. Org Biomol Chem. 2016. PMID: 27853797
15 results