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The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF. Evans CM, et al. Among authors: eltzschig hk. Nat Commun. 2015 Feb 17;6:6281. doi: 10.1038/ncomms7281. Nat Commun. 2015. PMID: 25687754 Free PMC article.
Detrimental effects of adenosine signaling in sickle cell disease.
Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Zhang Y, et al. Among authors: eltzschig hk. Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19. Nat Med. 2011. PMID: 21170046 Free PMC article.
The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease.
Karmouty-Quintana H, Zhong H, Acero L, Weng T, Melicoff E, West JD, Hemnes A, Grenz A, Eltzschig HK, Blackwell TS, Xia Y, Johnston RA, Zeng D, Belardinelli L, Blackburn MR. Karmouty-Quintana H, et al. Among authors: eltzschig hk. FASEB J. 2012 Jun;26(6):2546-57. doi: 10.1096/fj.11-200907. Epub 2012 Mar 13. FASEB J. 2012. PMID: 22415303 Free PMC article.
Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury.
Koeppen M, McNamee EN, Brodsky KS, Aherne CM, Faigle M, Downey GP, Colgan SP, Evans CM, Schwartz DA, Eltzschig HK. Koeppen M, et al. Among authors: eltzschig hk. Mucosal Immunol. 2013 Jul;6(4):762-75. doi: 10.1038/mi.2012.114. Epub 2012 Nov 28. Mucosal Immunol. 2013. PMID: 23187315 Free PMC article.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y. Zhang W, et al. Among authors: eltzschig hk. Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12. Circ Res. 2013. PMID: 23584256 Free PMC article.
Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension.
Karmouty-Quintana H, Philip K, Acero LF, Chen NY, Weng T, Molina JG, Luo F, Davies J, Le NB, Bunge I, Volcik KA, Le TT, Johnston RA, Xia Y, Eltzschig HK, Blackburn MR. Karmouty-Quintana H, et al. Among authors: eltzschig hk. FASEB J. 2015 Jan;29(1):50-60. doi: 10.1096/fj.14-260182. Epub 2014 Oct 15. FASEB J. 2015. PMID: 25318478 Free PMC article.
333 results