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Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening.
Kutchukian PS, Warren L, Magliaro BC, Amoss A, Cassaday JA, O'Donnell G, Squadroni B, Zuck P, Pascarella D, Culberson JC, Cooke AJ, Hurzy D, Schlegel KS, Thomson F, Johnson EN, Uebele VN, Hermes JD, Parmentier-Batteur S, Finley M. Kutchukian PS, et al. Among authors: hermes jd. ACS Chem Biol. 2017 Feb 17;12(2):519-527. doi: 10.1021/acschembio.6b00913. Epub 2017 Jan 6. ACS Chem Biol. 2017. PMID: 28032990 Free article.
Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN. Severyn B, et al. J Biomol Screen. 2016 Oct;21(9):989-97. doi: 10.1177/1087057116658646. Epub 2016 Jul 26. J Biomol Screen. 2016. PMID: 27461835
High-Content Reporter Assays.
Cook E, Hermes J, Li J, Tudor M. Cook E, et al. Methods Mol Biol. 2018;1755:179-195. doi: 10.1007/978-1-4939-7724-6_13. Methods Mol Biol. 2018. PMID: 29671271
Endogenous Locus Reporter Assays.
Liu Y, Hermes J, Li J, Tudor M. Liu Y, et al. Methods Mol Biol. 2018;1755:163-177. doi: 10.1007/978-1-4939-7724-6_12. Methods Mol Biol. 2018. PMID: 29671270
Translatability: what does it mean in drug discovery?
Tudor M, Hermes J, Li J. Tudor M, et al. Drug Discov Today. 2016 Jun;21(6):865-7. doi: 10.1016/j.drudis.2016.03.010. Epub 2016 Mar 26. Drug Discov Today. 2016. PMID: 27021791 No abstract available.
63 results