Kempema AM - Search Results

1

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer.

Brand LJ, Olson ME, Ravindranathan P, Guo H, Kempema AM, Andrews TE, Chen X, Raj GV, Harki DA, Dehm SM. Brand LJ, et al. Among authors: kempema am. Oncotarget. 2015 Feb 28;6(6):3811-24. doi: 10.18632/oncotarget.2924. Oncotarget. 2015. PMID: 25669987 Free PMC article.

2

Parthenolide prodrug LC-1 slows growth of intracranial glioma.

Hexum JK, Becker CM, Kempema AM, Ohlfest JR, Largaespada DA, Harki DA. Hexum JK, et al. Among authors: kempema am. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2493-5. doi: 10.1016/j.bmcl.2015.04.058. Epub 2015 Apr 25. Bioorg Med Chem Lett. 2015. PMID: 25978958

3

Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues.

Kempema AM, Widen JC, Hexum JK, Andrews TE, Wang D, Rathe SK, Meece FA, Noble KE, Sachs Z, Largaespada DA, Harki DA. Kempema AM, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4737-4745. doi: 10.1016/j.bmc.2015.05.037. Epub 2015 May 30. Bioorg Med Chem. 2015. PMID: 26088334 Free PMC article.

4

Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile.

Widen JC, Kempema AM, Villalta PW, Harki DA. Widen JC, et al. Among authors: kempema am. ACS Chem Biol. 2017 Jan 20;12(1):102-113. doi: 10.1021/acschembio.6b00751. Epub 2016 Nov 28. ACS Chem Biol. 2017. PMID: 28103680 Free PMC article.

5

Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles.

Widen JC, Kempema AM, Baur JW, Skopec HM, Edwards JT, Brown TJ, Brown DA, Meece FA, Harki DA. Widen JC, et al. Among authors: kempema am. ChemMedChem. 2018 Feb 20;13(4):303-311. doi: 10.1002/cmdc.201700752. Epub 2018 Jan 19. ChemMedChem. 2018. PMID: 29349898 Free PMC article.

6

Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle.

Kerr JP, Robison P, Shi G, Bogush AI, Kempema AM, Hexum JK, Becerra N, Harki DA, Martin SS, Raiteri R, Prosser BL, Ward CW. Kerr JP, et al. Among authors: kempema am. Nat Commun. 2015 Oct 8;6:8526. doi: 10.1038/ncomms9526. Nat Commun. 2015. PMID: 26446751 Free PMC article.

7

Specificity and Ligand Affinities of the Cocaine Aptamer: Impact of Structural Features and Physiological NaCl.

Sachan A, Ilgu M, Kempema A, Kraus GA, Nilsen-Hamilton M. Sachan A, et al. Anal Chem. 2016 Aug 2;88(15):7715-23. doi: 10.1021/acs.analchem.6b01633. Epub 2016 Jul 11. Anal Chem. 2016. PMID: 27348073

8

Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues.

Nicolaou KC, Shelke YG, Dherange BD, Kempema A, Lin B, Gu C, Sandoval J, Hammond M, Aujay M, Gavrilyuk J. Nicolaou KC, et al. J Org Chem. 2020 Mar 6;85(5):2865-2917. doi: 10.1021/acs.joc.0c00123. Epub 2020 Feb 17. J Org Chem. 2020. PMID: 32065746

9

A convenient synthesis of Type A procyanidins.

Kraus GA, Yuan Y, Kempema A. Kraus GA, et al. Molecules. 2009 Feb 17;14(2):807-15. doi: 10.3390/molecules14020807. Molecules. 2009. PMID: 19223829 Free PMC article.

10

Synthesis of azafluorenone antimicrobial agents.

Kraus GA, Kempema A. Kraus GA, et al. J Nat Prod. 2010 Nov 29;73(11):1967-8. doi: 10.1021/np100536a. Epub 2010 Oct 21. J Nat Prod. 2010. PMID: 20964320

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