Legen I - Search Results

1

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Levetiracetam.

Petruševska M, Berglez S, Krisch I, Legen I, Megušar K, Peternel L, Abrahamsson B, Cristofoletti R, Groot DW, Kopp S, Langguth P, Mehta M, Polli JE, Shah VP, Dressman J. Petruševska M, et al. Among authors: legen i. J Pharm Sci. 2015 Sep;104(9):2676-87. doi: 10.1002/jps.24350. Epub 2015 Feb 6. J Pharm Sci. 2015. PMID: 25663270 Review.

2

Suitability of isolated rat jejunum model for demonstration of complete absorption in humans for BCS-based biowaiver request.

Peternel L, Kristan K, Petruševska M, Rižner TL, Legen I. Peternel L, et al. Among authors: legen i. J Pharm Sci. 2012 Apr;101(4):1436-49. doi: 10.1002/jps.23027. Epub 2012 Jan 10. J Pharm Sci. 2012. PMID: 22234826

3

Determining the polymer threshold amount for achieving robust drug release from HPMC and HPC matrix tablets containing a high-dose BCS class I model drug: in vitro and in vivo studies.

Klančar U, Baumgartner S, Legen I, Smrdel P, Kampuš NJ, Krajcar D, Markun B, Kočevar K. Klančar U, et al. Among authors: legen i. AAPS PharmSciTech. 2015 Apr;16(2):398-406. doi: 10.1208/s12249-014-0234-4. Epub 2014 Oct 18. AAPS PharmSciTech. 2015. PMID: 25331194 Free PMC article. Clinical Trial.

4

The biorelevant simulation of gastric emptying and its impact on model drug dissolution and absorption kinetics.

Vrbanac H, Trontelj J, Berglez S, Petek B, Opara J, Jereb R, Krajcar D, Legen I. Vrbanac H, et al. Among authors: legen i. Eur J Pharm Biopharm. 2020 Apr;149:113-120. doi: 10.1016/j.ejpb.2020.02.002. Epub 2020 Feb 10. Eur J Pharm Biopharm. 2020. PMID: 32057907

5

Physiologically based absorption modeling to predict bioequivalence of controlled release and immediate release oral products.

Mitra A, Petek B, Bajc A, Velagapudi R, Legen I. Mitra A, et al. Among authors: legen i. Eur J Pharm Biopharm. 2019 Jan;134:117-125. doi: 10.1016/j.ejpb.2018.11.019. Epub 2018 Nov 22. Eur J Pharm Biopharm. 2019. PMID: 30472143

6

In vitro-In vivo Relationship and Bioequivalence Prediction for Modified-Release Capsules Based on a PBPK Absorption Model.

Jereb R, Opara J, Legen I, Petek B, Grabnar-Peklar D. Jereb R, et al. Among authors: legen i. AAPS PharmSciTech. 2019 Dec 9;21(1):18. doi: 10.1208/s12249-019-1566-x. AAPS PharmSciTech. 2019. PMID: 31820131

7

Biopharmaceutical classification of desloratadine - not all drugs are classified the easy way.

Berginc K, Sibinovska N, Žakelj S, Trontelj J, Legen I. Berginc K, et al. Among authors: legen i. Acta Pharm. 2020 Jun 1;70(2):131-144. doi: 10.2478/acph-2020-0006. Acta Pharm. 2020. PMID: 31955139 Free article.

8

D-glucose triggers multidrug resistance-associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro.

Legen I, Kristl A. Legen I, et al. Pharm Res. 2004 Apr;21(4):635-40. doi: 10.1023/b:pham.0000022410.89709.c3. Pharm Res. 2004. PMID: 15139520

9

A novel beads-based dissolution method for the in vitro evaluation of extended release HPMC matrix tablets and the correlation with the in vivo data.

Klančar U, Markun B, Baumgartner S, Legen I. Klančar U, et al. Among authors: legen i. AAPS J. 2013 Jan;15(1):267-77. doi: 10.1208/s12248-012-9422-x. Epub 2012 Nov 28. AAPS J. 2013. PMID: 23188526 Free PMC article. Clinical Trial.

10

Factors affecting the microclimate pH of the rat jejunum in ringer bicarbonate buffer.

Legen I, Kristl A. Legen I, et al. Biol Pharm Bull. 2003 Jun;26(6):886-9. doi: 10.1248/bpb.26.886. Biol Pharm Bull. 2003. PMID: 12808306 Free article.

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