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The autophagic machinery ensures nonlytic transmission of mycobacteria.
Gerstenmaier L, Pilla R, Herrmann L, Herrmann H, Prado M, Villafano GJ, Kolonko M, Reimer R, Soldati T, King JS, Hagedorn M. Gerstenmaier L, et al. Among authors: king js. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E687-92. doi: 10.1073/pnas.1423318112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646440 Free PMC article.
Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model.
Mesquita A, Cardenal-Muñoz E, Dominguez E, Muñoz-Braceras S, Nuñez-Corcuera B, Phillips BA, Tábara LC, Xiong Q, Coria R, Eichinger L, Golstein P, King JS, Soldati T, Vincent O, Escalante R. Mesquita A, et al. Among authors: king js. Autophagy. 2017 Jan 2;13(1):24-40. doi: 10.1080/15548627.2016.1226737. Epub 2016 Oct 7. Autophagy. 2017. PMID: 27715405 Free PMC article. Review.
Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner.
Cardenal-Muñoz E, Arafah S, López-Jiménez AT, Kicka S, Falaise A, Bach F, Schaad O, King JS, Hagedorn M, Soldati T. Cardenal-Muñoz E, et al. Among authors: king js. PLoS Pathog. 2017 Apr 17;13(4):e1006344. doi: 10.1371/journal.ppat.1006344. eCollection 2017 Apr. PLoS Pathog. 2017. PMID: 28414774 Free PMC article.
The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection.
López-Jiménez AT, Cardenal-Muñoz E, Leuba F, Gerstenmaier L, Barisch C, Hagedorn M, King JS, Soldati T. López-Jiménez AT, et al. Among authors: king js. PLoS Pathog. 2018 Dec 31;14(12):e1007501. doi: 10.1371/journal.ppat.1007501. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30596802 Free PMC article.
PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection.
Buckley CM, Heath VL, Guého A, Bosmani C, Knobloch P, Sikakana P, Personnic N, Dove SK, Michell RH, Meier R, Hilbi H, Soldati T, Insall RH, King JS. Buckley CM, et al. Among authors: king js. PLoS Pathog. 2019 Feb 7;15(2):e1007551. doi: 10.1371/journal.ppat.1007551. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30730983 Free PMC article.
342 results