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The autophagic machinery ensures nonlytic transmission of mycobacteria.
Gerstenmaier L, Pilla R, Herrmann L, Herrmann H, Prado M, Villafano GJ, Kolonko M, Reimer R, Soldati T, King JS, Hagedorn M. Gerstenmaier L, et al. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E687-92. doi: 10.1073/pnas.1423318112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646440 Free PMC article.
The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection.
López-Jiménez AT, Cardenal-Muñoz E, Leuba F, Gerstenmaier L, Barisch C, Hagedorn M, King JS, Soldati T. López-Jiménez AT, et al. Among authors: gerstenmaier l. PLoS Pathog. 2018 Dec 31;14(12):e1007501. doi: 10.1371/journal.ppat.1007501. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30596802 Free PMC article.