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Tumour suppressor TRIM33 targets nuclear β-catenin degradation.
Xue J, Chen Y, Wu Y, Wang Z, Zhou A, Zhang S, Lin K, Aldape K, Majumder S, Lu Z, Huang S. Xue J, et al. Among authors: chen y. Nat Commun. 2015 Feb 2;6:6156. doi: 10.1038/ncomms7156. Nat Commun. 2015. PMID: 25639486 Free PMC article.
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
Wei S, Yin D, Yu S, Lin X, Savani MR, Du K, Ku Y, Wu D, Li S, Liu H, Tian M, Chen Y, Bowie M, Hariharan S, Waitkus M, Keir ST, Sugarman ET, Deek RA, Labrie M, Khasraw M, Lu Y, Mills GB, Herlyn M, Wu K, Liu L, Wei Z, Flaherty KT, Abdullah K, Zhang G, Ashley DM. Wei S, et al. Among authors: chen y. Clin Cancer Res. 2022 May 13;28(10):2180-2195. doi: 10.1158/1078-0432.CCR-21-0833. Clin Cancer Res. 2022. PMID: 35247901 Free PMC article.
Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors.
George J, Chen Y, Abdelfattah N, Yamamoto K, Gallup TD, Adamson SI, Rybinski B, Srivastava A, Kumar P, Lee MG, Baskin DS, Jiang W, Choi JM, Flavahan W, Chuang JH, Kim BY, Xu J, Jung SY, Yun K. George J, et al. Among authors: chen y. Cancer Res Commun. 2022 Jun;2(6):402-416. doi: 10.1158/2767-9764.crc-22-0124. Epub 2022 Jun 6. Cancer Res Commun. 2022. PMID: 36688010 Free PMC article.
A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
Yu S, Wei S, Savani M, Lin X, Du K, Mender I, Siteni S, Vasilopoulos T, Reitman ZJ, Ku Y, Wu D, Liu H, Tian M, Chen Y, Labrie M, Charbonneau CM, Sugarman E, Bowie M, Hariharan S, Waitkus M, Jiang W, McLendon RE, Pan E, Khasraw M, Walsh KM, Lu Y, Herlyn M, Mills G, Herbig U, Wei Z, Keir ST, Flaherty K, Liu L, Wu K, Shay JW, Abdullah K, Zhang G, Ashley DM. Yu S, et al. Among authors: chen y. Clin Cancer Res. 2021 Dec 15;27(24):6800-6814. doi: 10.1158/1078-0432.CCR-21-0374. Epub 2021 Sep 30. Clin Cancer Res. 2021. PMID: 34593527 Free PMC article.
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