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Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity.
Amoah A, Keller A, Emini R, Hoenicka M, Liebold A, Vollmer A, Eiwen K, Soller K, Sakk V, Zheng Y, Florian MC, Geiger H. Amoah A, et al. Among authors: sakk v. Haematologica. 2022 Feb 1;107(2):393-402. doi: 10.3324/haematol.2020.269670. Haematologica. 2022. PMID: 33440922 Free PMC article.
A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells.
Tiwari RL, Mishra P, Martin N, George NO, Sakk V, Soller K, Nalapareddy K, Nattamai K, Scharffetter-Kochanek K, Florian MC, Geiger H. Tiwari RL, et al. Among authors: sakk v. Aging (Albany NY). 2021 Feb 25;13(4):4778-4793. doi: 10.18632/aging.202694. Epub 2021 Feb 25. Aging (Albany NY). 2021. PMID: 33629967 Free PMC article.
Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.
Kandi R, Senger K, Grigoryan A, Soller K, Sakk V, Schuster T, Eiwen K, Menon MB, Gaestel M, Zheng Y, Florian MC, Geiger H. Kandi R, et al. Among authors: sakk v. EMBO Rep. 2021 Dec 6;22(12):e52931. doi: 10.15252/embr.202152931. Epub 2021 Oct 18. EMBO Rep. 2021. PMID: 34661963 Free PMC article.
Reduced adhesion of aged intestinal stem cells contributes to an accelerated clonal drift.
Hageb A, Thalheim T, Nattamai KJ, Möhrle B, Saçma M, Sakk V, Thielecke L, Cornils K, Grandy C, Port F, Gottschalk KE, Mallm JP, Glauche I, Galle J, Mulaw MA, Geiger H. Hageb A, et al. Among authors: sakk v. Life Sci Alliance. 2022 Apr 29;5(8):e202201408. doi: 10.26508/lsa.202201408. Print 2022 Aug. Life Sci Alliance. 2022. PMID: 35487692 Free PMC article.
27 results