Ecker G - Search Results

1

Synthesis and in silico evaluation of novel compounds for PET-based investigations of the norepinephrine transporter.

Neudorfer C, Seddik A, Shanab K, Jurik A, Rami-Mark C, Holzer W, Ecker G, Mitterhauser M, Wadsak W, Spreitzer H. Neudorfer C, et al. Among authors: ecker g. Molecules. 2015 Jan 20;20(1):1712-30. doi: 10.3390/molecules20011712. Molecules. 2015. PMID: 25608857 Free PMC article.

2

Substituted 4-acylpyrazoles and 4-acylpyrazolones: synthesis and multidrug resistance-modulating activity.

Chiba P, Holzer W, Landau M, Bechmann G, Lorenz K, Plagens B, Hitzler M, Richter E, Ecker G. Chiba P, et al. Among authors: ecker g. J Med Chem. 1998 Oct 8;41(21):4001-11. doi: 10.1021/jm980121y. J Med Chem. 1998. PMID: 9767638

3

Identification of ligand-binding regions of P-glycoprotein by activated-pharmacophore photoaffinity labeling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.

Ecker GF, Csaszar E, Kopp S, Plagens B, Holzer W, Ernst W, Chiba P. Ecker GF, et al. Mol Pharmacol. 2002 Mar;61(3):637-48. doi: 10.1124/mol.61.3.637. Mol Pharmacol. 2002. PMID: 11854445

4

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate.

Buchmayer F, Schicker K, Steinkellner T, Geier P, Stübiger G, Hamilton PJ, Jurik A, Stockner T, Yang JW, Montgomery T, Holy M, Hofmaier T, Kudlacek O, Matthies HJ, Ecker GF, Bochkov V, Galli A, Boehm S, Sitte HH. Buchmayer F, et al. Among authors: ecker gf. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11642-7. doi: 10.1073/pnas.1220552110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798435 Free PMC article.

5

Probing the Selectivity of Monoamine Transporter Substrates by Means of Molecular Modeling.

Seddik A, Holy M, Weissensteiner R, Zdrazil B, Sitte HH, Ecker GF. Seddik A, et al. Mol Inform. 2013 Jun;32(5-6):409-413. doi: 10.1002/minf.201300013. Epub 2013 Jun 12. Mol Inform. 2013. PMID: 23956802 Free PMC article. No abstract available.

6

Classification of High-Activity Tiagabine Analogs by Binary QSAR Modeling.

Jurik A, Reicherstorfer R, Zdrazil B, Ecker GF. Jurik A, et al. Mol Inform. 2013 Jun;32(5-6):415-419. doi: 10.1002/minf.201300020. Epub 2013 May 15. Mol Inform. 2013. PMID: 23956803 Free PMC article. No abstract available.

7

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters.

Hofmaier T, Luf A, Seddik A, Stockner T, Holy M, Freissmuth M, Ecker GF, Schmid R, Sitte HH, Kudlacek O. Hofmaier T, et al. Neurochem Int. 2014 Jul;73(100):32-41. doi: 10.1016/j.neuint.2013.11.010. Epub 2013 Dec 1. Neurochem Int. 2014. PMID: 24296074 Free PMC article.

8

Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer's disease.

Neudorfer C, Shanab K, Jurik A, Schreiber V, Neudorfer C, Vraka C, Schirmer E, Holzer W, Ecker G, Mitterhauser M, Wadsak W, Spreitzer H. Neudorfer C, et al. Among authors: ecker g. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4490-4495. doi: 10.1016/j.bmcl.2014.07.085. Epub 2014 Aug 7. Bioorg Med Chem Lett. 2014. PMID: 25127869

9

'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function.

Saha K, Partilla JS, Lehner KR, Seddik A, Stockner T, Holy M, Sandtner W, Ecker GF, Sitte HH, Baumann MH. Saha K, et al. Neuropsychopharmacology. 2015 May;40(6):1321-31. doi: 10.1038/npp.2014.325. Epub 2014 Dec 15. Neuropsychopharmacology. 2015. PMID: 25502630 Free PMC article.

10

A binding mode hypothesis of tiagabine confirms liothyronine effect on γ-aminobutyric acid transporter 1 (GAT1).

Jurik A, Zdrazil B, Holy M, Stockner T, Sitte HH, Ecker GF. Jurik A, et al. J Med Chem. 2015 Mar 12;58(5):2149-58. doi: 10.1021/jm5015428. Epub 2015 Feb 26. J Med Chem. 2015. PMID: 25679268 Free PMC article.

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