Aubé J - Search Results

1

Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif.

Frankowski KJ, Slauson SR, Lovell KM, Phillips AM, Streicher JM, Zhou L, Whipple DA, Schoenen FJ, Prisinzano TE, Bohn LM, Aubé J. Frankowski KJ, et al. Among authors: aube j. Bioorg Med Chem. 2015 Jul 15;23(14):3948-56. doi: 10.1016/j.bmc.2014.12.033. Epub 2014 Dec 23. Bioorg Med Chem. 2015. PMID: 25593096 Free PMC article.

2

Butitaxel analogues: synthesis and structure-activity relationships.

Ali SM, Hoemann MZ, Aubé J, Georg GI, Mitscher LA, Jayasinghe LR. Ali SM, et al. Among authors: aube j. J Med Chem. 1997 Jan 17;40(2):236-41. doi: 10.1021/jm960505t. J Med Chem. 1997. PMID: 9003522

3

Synthesis and evaluation of peptidyl Michael acceptors that inactivate human rhinovirus 3C protease and inhibit virus replication.

Kong JS, Venkatraman S, Furness K, Nimkar S, Shepherd TA, Wang QM, Aubé J, Hanzlik RP. Kong JS, et al. Among authors: aube j. J Med Chem. 1998 Jul 2;41(14):2579-87. doi: 10.1021/jm980114+. J Med Chem. 1998. PMID: 9651162

4

Synthesis of a small library of diketopiperazines as potential inhibitors of calpain.

Zeng Y, Li Q, Hanzlik RP, Aubé J. Zeng Y, et al. Among authors: aube j. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3034-8. doi: 10.1016/j.bmcl.2005.04.031. Bioorg Med Chem Lett. 2005. PMID: 15896956

5

Solution-phase parallel synthesis of a library of delta(2)-pyrazolines.

Manyem S, Sibi MP, Lushington GH, Neuenswander B, Schoenen F, Aubé J. Manyem S, et al. Among authors: aube j. J Comb Chem. 2007 Jan-Feb;9(1):20-8. doi: 10.1021/cc0601175. J Comb Chem. 2007. PMID: 17206829 Free PMC article.

6

One-step synthesis of oxazoline and dihydrooxazine libraries.

Chaudhry P, Schoenen F, Neuenswander B, Lushington GH, Aubé J. Chaudhry P, et al. Among authors: aube j. J Comb Chem. 2007 May-Jun;9(3):473-6. doi: 10.1021/cc060159t. Epub 2007 Mar 29. J Comb Chem. 2007. PMID: 17391008 Free PMC article.

7

Synthesis of N-alkyl-octahydroisoquinolin-1-one-8-carboxamide libraries using a tandem Diels-Alder/acylation sequence.

Frankowski KJ, Hirt EE, Zeng Y, Neuenswander B, Fowler D, Schoenen F, Aubé J. Frankowski KJ, et al. Among authors: aube j. J Comb Chem. 2007 Nov-Dec;9(6):1188-92. doi: 10.1021/cc700127f. Epub 2007 Sep 27. J Comb Chem. 2007. PMID: 17896822

8

Three-component synthesis of 1,4-diazepin-5-ones and the construction of gamma-turn-like peptidomimetic libraries.

Fenster E, Rayabarapu DK, Zhang M, Mukherjee S, Hill D, Neuenswander B, Schoenen F, Hanson PR, Aubé J. Fenster E, et al. Among authors: aube j. J Comb Chem. 2008 Mar-Apr;10(2):230-4. doi: 10.1021/cc700174c. Epub 2008 Feb 7. J Comb Chem. 2008. PMID: 18254600

9

Efficient synthesis of gamma-lactams by a tandem reductive amination/lactamization sequence.

Nöth J, Frankowski KJ, Neuenswander B, Aubé J, Reiser O. Nöth J, et al. Among authors: aube j. J Comb Chem. 2008 May-Jun;10(3):456-9. doi: 10.1021/cc700202c. Epub 2008 Mar 14. J Comb Chem. 2008. PMID: 18338857 Free PMC article.

10

Syntheses of the Stemona alkaloids (+/-)-stenine, (+/-)-neostenine, and (+/-)-13-epineostenine using a stereodivergent Diels-Alder/azido-Schmidt reaction.

Frankowski KJ, Golden JE, Zeng Y, Lei Y, Aubé J. Frankowski KJ, et al. Among authors: aube j. J Am Chem Soc. 2008 May 7;130(18):6018-24. doi: 10.1021/ja800574m. Epub 2008 Apr 9. J Am Chem Soc. 2008. PMID: 18396881 Free PMC article.

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