Murrey HE - Search Results

1

Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin.

Pettersson M, Johnson DS, Humphrey JM, Am Ende CW, Evrard E, Efremov I, Kauffman GW, Stepan AF, Stiff CM, Xie L, Bales KR, Hajos-Korcsok E, Murrey HE, Pustilnik LR, Steyn SJ, Wood KM, Verhoest PR. Pettersson M, et al. Among authors: murrey he. Bioorg Med Chem Lett. 2015 Feb 15;25(4):908-13. doi: 10.1016/j.bmcl.2014.12.059. Epub 2014 Dec 25. Bioorg Med Chem Lett. 2015. PMID: 25582600

2

γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin.

Pozdnyakov N, Murrey HE, Crump CJ, Pettersson M, Ballard TE, Am Ende CW, Ahn K, Li YM, Bales KR, Johnson DS. Pozdnyakov N, et al. Among authors: murrey he. J Biol Chem. 2013 Apr 5;288(14):9710-9720. doi: 10.1074/jbc.M112.398602. Epub 2013 Feb 8. J Biol Chem. 2013. PMID: 23396974 Free PMC article.

3

Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase.

Crump CJ, Murrey HE, Ballard TE, Am Ende CW, Wu X, Gertsik N, Johnson DS, Li YM. Crump CJ, et al. Among authors: murrey he. ACS Chem Neurosci. 2016 Aug 17;7(8):1166-73. doi: 10.1021/acschemneuro.6b00127. Epub 2016 Jun 17. ACS Chem Neurosci. 2016. PMID: 27253220 Free PMC article.

4

Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging.

Murrey HE, Judkins JC, Am Ende CW, Ballard TE, Fang Y, Riccardi K, Di L, Guilmette ER, Schwartz JW, Fox JM, Johnson DS. Murrey HE, et al. J Am Chem Soc. 2015 Sep 9;137(35):11461-75. doi: 10.1021/jacs.5b06847. Epub 2015 Aug 31. J Am Chem Soc. 2015. PMID: 26270632 Free PMC article.

5

Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.

Tichenor MS, Wiener JJM, Rao NL, Pooley Deckhut C, Barbay JK, Kreutter KD, Bacani GM, Wei J, Chang L, Murrey HE, Wang W, Ahn K, Huber M, Rex E, Coe KJ, Wu J, Seierstad M, Bembenek SD, Leonard KA, Lebsack AD, Venable JD, Edwards JP. Tichenor MS, et al. Among authors: murrey he. ACS Med Chem Lett. 2021 Apr 5;12(5):782-790. doi: 10.1021/acsmedchemlett.1c00044. eCollection 2021 May 13. ACS Med Chem Lett. 2021. PMID: 34055226 Free PMC article.

6

Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways.

Tsao TS, Tomas E, Murrey HE, Hug C, Lee DH, Ruderman NB, Heuser JE, Lodish HF. Tsao TS, et al. Among authors: murrey he. J Biol Chem. 2003 Dec 12;278(50):50810-7. doi: 10.1074/jbc.M309469200. Epub 2003 Sep 30. J Biol Chem. 2003. PMID: 14522956 Free article.

7

Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30).

Tsao TS, Murrey HE, Hug C, Lee DH, Lodish HF. Tsao TS, et al. Among authors: murrey he. J Biol Chem. 2002 Aug 16;277(33):29359-62. doi: 10.1074/jbc.C200312200. Epub 2002 Jun 26. J Biol Chem. 2002. PMID: 12087086 Free article.

8

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation.

Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc Cc, Itani SI, Lodish HF, Ruderman NB. Tomas E, et al. Among authors: murrey he. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16309-13. doi: 10.1073/pnas.222657499. Epub 2002 Nov 27. Proc Natl Acad Sci U S A. 2002. PMID: 12456889 Free PMC article.

9

Monomeric 14-3-3 protein is sufficient to modulate the activity of the Drosophila slowpoke calcium-dependent potassium channel.

Zhou Y, Reddy S, Murrey H, Fei H, Levitan IB. Zhou Y, et al. J Biol Chem. 2003 Mar 21;278(12):10073-80. doi: 10.1074/jbc.M211907200. Epub 2003 Jan 15. J Biol Chem. 2003. PMID: 12529354 Free article.

10

A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals.

Zhou Y, Schopperle WM, Murrey H, Jaramillo A, Dagan D, Griffith LC, Levitan IB. Zhou Y, et al. Neuron. 1999 Apr;22(4):809-18. doi: 10.1016/s0896-6273(00)80739-4. Neuron. 1999. PMID: 10230800 Free article.

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