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PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma.
Majuelos-Melguizo J, Rodríguez MI, López-Jiménez L, Rodríguez-Vargas JM, Martí Martín-Consuegra JM, Serrano-Sáenz S, Gavard J, de Almodóvar JM, Oliver FJ. Majuelos-Melguizo J, et al. Among authors: oliver fj. Oncotarget. 2015 Mar 10;6(7):4790-803. doi: 10.18632/oncotarget.2993. Oncotarget. 2015. PMID: 25576921 Free PMC article.
Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation.
Aguilar-Quesada R, Muñoz-Gámez JA, Martín-Oliva D, Peralta-Leal A, Quiles-Pérez R, Rodríguez-Vargas JM, Ruiz de Almodóvar M, Conde C, Ruiz-Extremera A, Oliver FJ. Aguilar-Quesada R, et al. Among authors: oliver fj. Curr Med Chem. 2007;14(11):1179-87. doi: 10.2174/092986707780597998. Curr Med Chem. 2007. PMID: 17504138 Review.
PARP-1 is involved in autophagy induced by DNA damage.
Muñoz-Gámez JA, Rodríguez-Vargas JM, Quiles-Pérez R, Aguilar-Quesada R, Martín-Oliva D, de Murcia G, Menissier de Murcia J, Almendros A, Ruiz de Almodóvar M, Oliver FJ. Muñoz-Gámez JA, et al. Among authors: oliver fj. Autophagy. 2009 Jan;5(1):61-74. doi: 10.4161/auto.5.1.7272. Epub 2009 Jan 27. Autophagy. 2009. PMID: 19001878
PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.
Peralta-Leal A, Rodríguez-Vargas JM, Aguilar-Quesada R, Rodríguez MI, Linares JL, de Almodóvar MR, Oliver FJ. Peralta-Leal A, et al. Among authors: oliver fj. Free Radic Biol Med. 2009 Jul 1;47(1):13-26. doi: 10.1016/j.freeradbiomed.2009.04.008. Epub 2009 Apr 10. Free Radic Biol Med. 2009. PMID: 19362586 Review.
Poly(ADP-ribose)-dependent regulation of Snail1 protein stability.
Rodríguez MI, González-Flores A, Dantzer F, Collard J, de Herreros AG, Oliver FJ. Rodríguez MI, et al. Among authors: oliver fj. Oncogene. 2011 Oct 20;30(42):4365-72. doi: 10.1038/onc.2011.153. Epub 2011 May 16. Oncogene. 2011. PMID: 21577210
ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy.
Rodríguez-Vargas JM, Ruiz-Magaña MJ, Ruiz-Ruiz C, Majuelos-Melguizo J, Peralta-Leal A, Rodríguez MI, Muñoz-Gámez JA, de Almodóvar MR, Siles E, Rivas AL, Jäättela M, Oliver FJ. Rodríguez-Vargas JM, et al. Among authors: oliver fj. Cell Res. 2012 Jul;22(7):1181-98. doi: 10.1038/cr.2012.70. Epub 2012 Apr 24. Cell Res. 2012. PMID: 22525338 Free PMC article.
Poly(ADP-ribose) signaling in cell death.
Virág L, Robaszkiewicz A, Rodriguez-Vargas JM, Oliver FJ. Virág L, et al. Among authors: oliver fj. Mol Aspects Med. 2013 Dec;34(6):1153-67. doi: 10.1016/j.mam.2013.01.007. Epub 2013 Feb 15. Mol Aspects Med. 2013. PMID: 23416893 Review.
Interaction between PARP-1 and HIF-2α in the hypoxic response.
Gonzalez-Flores A, Aguilar-Quesada R, Siles E, Pozo S, Rodríguez-Lara MI, López-Jiménez L, López-Rodríguez M, Peralta-Leal A, Villar D, Martín-Oliva D, del Peso L, Berra E, Oliver FJ. Gonzalez-Flores A, et al. Among authors: oliver fj. Oncogene. 2014 Feb 13;33(7):891-8. doi: 10.1038/onc.2013.9. Epub 2013 Mar 4. Oncogene. 2014. PMID: 23455322
PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation.
Rodríguez MI, Peralta-Leal A, O'Valle F, Rodriguez-Vargas JM, Gonzalez-Flores A, Majuelos-Melguizo J, López L, Serrano S, de Herreros AG, Rodríguez-Manzaneque JC, Fernández R, Del Moral RG, de Almodóvar JM, Oliver FJ. Rodríguez MI, et al. Among authors: oliver fj. PLoS Genet. 2013 Jun;9(6):e1003531. doi: 10.1371/journal.pgen.1003531. Epub 2013 Jun 13. PLoS Genet. 2013. PMID: 23785295 Free PMC article.
111 results