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Transdermal deferoxamine prevents pressure-induced diabetic ulcers.
Duscher D, Neofytou E, Wong VW, Maan ZN, Rennert RC, Inayathullah M, Januszyk M, Rodrigues M, Malkovskiy AV, Whitmore AJ, Walmsley GG, Galvez MG, Whittam AJ, Brownlee M, Rajadas J, Gurtner GC. Duscher D, et al. Among authors: brownlee m. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):94-9. doi: 10.1073/pnas.1413445112. Epub 2014 Dec 22. Proc Natl Acad Sci U S A. 2015. PMID: 25535360 Free PMC article.
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues.
Thangarajah H, Yao D, Chang EI, Shi Y, Jazayeri L, Vial IN, Galiano RD, Du XL, Grogan R, Galvez MG, Januszyk M, Brownlee M, Gurtner GC. Thangarajah H, et al. Among authors: brownlee m. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13505-10. doi: 10.1073/pnas.0906670106. Epub 2009 Jul 28. Proc Natl Acad Sci U S A. 2009. PMID: 19666581 Free PMC article.
HIF-1alpha dysfunction in diabetes.
Thangarajah H, Vial IN, Grogan RH, Yao D, Shi Y, Januszyk M, Galiano RD, Chang EI, Galvez MG, Glotzbach JP, Wong VW, Brownlee M, Gurtner GC. Thangarajah H, et al. Among authors: brownlee m. Cell Cycle. 2010 Jan 1;9(1):75-9. doi: 10.4161/cc.9.1.10371. Cell Cycle. 2010. PMID: 20016290
Small molecule inhibition of dipeptidyl peptidase-4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds.
Whittam AJ, Maan ZN, Duscher D, Barrera JA, Hu MS, Fischer LH, Khong S, Kwon SH, Wong VW, Walmsley GG, Giacco F, Januszyk M, Brownlee M, Longaker MT, Gurtner GC. Whittam AJ, et al. Among authors: brownlee m. Transl Res. 2019 Mar;205:51-63. doi: 10.1016/j.trsl.2018.10.006. Epub 2018 Nov 2. Transl Res. 2019. PMID: 30452888 Free PMC article.
Oxidative stress and diabetic complications.
Giacco F, Brownlee M. Giacco F, et al. Among authors: brownlee m. Circ Res. 2010 Oct 29;107(9):1058-70. doi: 10.1161/CIRCRESAHA.110.223545. Circ Res. 2010. PMID: 21030723 Free PMC article. Review.
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.
Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M. Du XL, et al. Among authors: brownlee m. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12222-6. doi: 10.1073/pnas.97.22.12222. Proc Natl Acad Sci U S A. 2000. PMID: 11050244 Free PMC article.
233 results