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Page 1
A general approach to antibody thermostabilization.
McConnell AD, Zhang X, Macomber JL, Chau B, Sheffer JC, Rahmanian S, Hare E, Spasojevic V, Horlick RA, King DJ, Bowers PM. McConnell AD, et al. Among authors: bowers pm. MAbs. 2014;6(5):1274-82. doi: 10.4161/mabs.29680. MAbs. 2014. PMID: 25517312 Free PMC article.
Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies.
Bowers PM, Horlick RA, Neben TY, Toobian RM, Tomlinson GL, Dalton JL, Jones HA, Chen A, Altobell L 3rd, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell A, Chau B, Holland T, Berkebile AD, Neben SS, Boyle WJ, King DJ. Bowers PM, et al. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20455-60. doi: 10.1073/pnas.1114010108. Epub 2011 Dec 7. Proc Natl Acad Sci U S A. 2011. PMID: 22158898 Free PMC article.
Mammalian cell display for the discovery and optimization of antibody therapeutics.
Bowers PM, Horlick RA, Kehry MR, Neben TY, Tomlinson GL, Altobell L, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell AD, Chau B, Berkebile AD, Hare E, Verdino P, King DJ. Bowers PM, et al. Methods. 2014 Jan 1;65(1):44-56. doi: 10.1016/j.ymeth.2013.06.010. Epub 2013 Jun 20. Methods. 2014. PMID: 23792919
High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation.
McConnell AD, Do M, Neben TY, Spasojevic V, MacLaren J, Chen AP, Altobell L 3rd, Macomber JL, Berkebile AD, Horlick RA, Bowers PM, King DJ. McConnell AD, et al. Among authors: bowers pm. PLoS One. 2012;7(11):e49458. doi: 10.1371/journal.pone.0049458. Epub 2012 Nov 14. PLoS One. 2012. PMID: 23166676 Free PMC article.
23 results