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Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine.
Webster R, Sekuloski S, Odedra A, Woolley S, Jennings H, Amante F, Trenholme KR, Healer J, Cowman AF, Eriksson EM, Sathe P, Penington J, Blanch AJ, Dixon MWA, Tilley L, Duffy MF, Craig A, Storm J, Chan JA, Evans K, Papenfuss AT, Schofield L, Griffin P, Barber BE, Andrew D, Boyle MJ, de Labastida Rivera F, Engwerda C, McCarthy JS. Webster R, et al. Among authors: trenholme kr. BMC Med. 2021 Nov 22;19(1):293. doi: 10.1186/s12916-021-02150-x. BMC Med. 2021. PMID: 34802442 Free PMC article. Clinical Trial.
Anti-Giardia Drug Discovery: Current Status and Gut Feelings.
Riches A, Hart CJS, Trenholme KR, Skinner-Adams TS. Riches A, et al. Among authors: trenholme kr. J Med Chem. 2020 Nov 25;63(22):13330-13354. doi: 10.1021/acs.jmedchem.0c00910. Epub 2020 Sep 16. J Med Chem. 2020. PMID: 32869995 Review.
The development of sexual stage malaria gametocytes in a Wave Bioreactor.
Demanga CG, Eng JWL, Gardiner DL, Roth A, Butterworth A, Adams JH, Trenholme KR, Dalton JP. Demanga CG, et al. Among authors: trenholme kr. Parasit Vectors. 2017 May 2;10(1):216. doi: 10.1186/s13071-017-2155-z. Parasit Vectors. 2017. PMID: 28464929 Free PMC article.
Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite.
Stanisic DI, Gerrard J, Fink J, Griffin PM, Liu XQ, Sundac L, Sekuloski S, Rodriguez IB, Pingnet J, Yang Y, Zhou Y, Trenholme KR, Wang CY, Hackett H, Chan JA, Langer C, Hanssen E, Hoffman SL, Beeson JG, McCarthy JS, Good MF. Stanisic DI, et al. Among authors: trenholme kr. Infect Immun. 2016 Aug 19;84(9):2689-96. doi: 10.1128/IAI.00414-16. Print 2016 Sep. Infect Immun. 2016. PMID: 27382019 Free PMC article.
A repeat sequence domain of the ring-exported protein-1 of Plasmodium falciparum controls export machinery architecture and virulence protein trafficking.
McHugh E, Batinovic S, Hanssen E, McMillan PJ, Kenny S, Griffin MD, Crawford S, Trenholme KR, Gardiner DL, Dixon MW, Tilley L. McHugh E, et al. Among authors: trenholme kr. Mol Microbiol. 2015 Dec;98(6):1101-14. doi: 10.1111/mmi.13201. Epub 2015 Sep 25. Mol Microbiol. 2015. PMID: 26304012 Free PMC article.
Plasmodium falciparum gametocytes: playing hide and seek.
Gardiner DL, Trenholme KR. Gardiner DL, et al. Among authors: trenholme kr. Ann Transl Med. 2015 Mar;3(4):45. doi: 10.3978/j.issn.2305-5839.2015.01.23. Ann Transl Med. 2015. PMID: 25861600 Free PMC article. No abstract available.
Inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase.
Schoenen FJ, Whipple D, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Hodder P, Mathew R, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Weiner WS, Aubé J, Rosen H, White EL, Gardiner DL, Dalton JP. Schoenen FJ, et al. Among authors: trenholme kr. 2013 Dec 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2013 Dec 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 25506973 Free Books & Documents. Review.
Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase.
Schoenen FJ, Weiner WS, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Ghosh P, Hodder P, Krise JP, Matharu DS, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Whipple D, Aubé J, Rosen H, White EL, Dalton JP, Gardiner DL. Schoenen FJ, et al. Among authors: trenholme kr. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24479194 Free Books & Documents. Review.
71 results