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Page 1
Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.
Ahmed SK, Haese NN, Cowan JT, Pathak V, Moukha-Chafiq O, Smith VJ, Rodzinak KJ, Ahmad F, Zhang S, Bonin KM, Streblow AD, Streblow CE, Kreklywich CN, Morrison C, Sarkar S, Moorman N, Sander W, Allen R, DeFilippis V, Tekwani BL, Wu M, Hirsch AJ, Smith JL, Tower NA, Rasmussen L, Bostwick R, Maddry JA, Ananthan S, Gerdes JM, Augelli-Szafran CE, Suto MJ, Morrison TE, Heise MT, Streblow DN, Pathak AK. Ahmed SK, et al. Among authors: tower na. J Med Chem. 2021 Apr 22;64(8):4762-4786. doi: 10.1021/acs.jmedchem.0c02183. Epub 2021 Apr 9. J Med Chem. 2021. PMID: 33835811 Free PMC article.
Studies on Dibenzylamines as Inhibitors of Venezuelan Equine Encephalitis Virus.
Nguyen TH, Haese NN, Madadi N, Sarkar S, Bonin K, Streblow CE, Taft-Benz S, Tower NA, Rasmussen L, Bostwick R, Augelli-Szafran CE, Suto MJ, Morrison TE, DeFilippis V, Heise MT, Streblow DN, Pathak AK. Nguyen TH, et al. Among authors: tower na. ACS Infect Dis. 2019 Dec 13;5(12):2014-2028. doi: 10.1021/acsinfecdis.9b00035. Epub 2019 Jul 11. ACS Infect Dis. 2019. PMID: 31257853
Mycobacterium tuberculosis High-Throughput Screening.
White EL, Tower NA, Rasmussen L. White EL, et al. Among authors: tower na. Methods Mol Biol. 2016;1439:181-95. doi: 10.1007/978-1-4939-3673-1_12. Methods Mol Biol. 2016. PMID: 27316996
Identification of a chemically validated target in replicating and non-replicating Mycobacterium tuberculosis with the aid of a small molecule probe.
Nag PP, Grant SS, Lewis TA, Gordon K, Kawate T, Fitzgerald M, Nietupski R, Gomez J, White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Sosa M, Rasmussen L, Johnston S, Bittker JA, Dandapani S, Perez J, Munoz B, Palmer M, Schreiber SL, Hung DT. Nag PP, et al. Among authors: tower na. 2014 Apr 15 [updated 2015 Jan 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2014 Apr 15 [updated 2015 Jan 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 25834898 Free Books & Documents. Review.
Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus.
Schroeder CE, Yao T, Sotsky J, Smith RA, Roy S, Chu YK, Guo H, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, Smith LH, White EL, Aubé J, Jonsson CB, Chung D, Golden JE. Schroeder CE, et al. Among authors: tower na. J Med Chem. 2014 Oct 23;57(20):8608-21. doi: 10.1021/jm501203v. Epub 2014 Oct 7. J Med Chem. 2014. PMID: 25244572 Free PMC article.
Inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase.
Schoenen FJ, Whipple D, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Hodder P, Mathew R, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Weiner WS, Aubé J, Rosen H, White EL, Gardiner DL, Dalton JP. Schoenen FJ, et al. Among authors: tower na. 2013 Dec 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2013 Dec 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 25506973 Free Books & Documents. Review.
Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase.
Schoenen FJ, Weiner WS, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Ghosh P, Hodder P, Krise JP, Matharu DS, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Whipple D, Aubé J, Rosen H, White EL, Dalton JP, Gardiner DL. Schoenen FJ, et al. Among authors: tower na. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24479194 Free Books & Documents. Review.
Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis.
Goller CC, Arshad M, Noah JW, Ananthan S, Evans CW, Nebane NM, Rasmussen L, Sosa M, Tower NA, White EL, Neuenswander B, Porubsky P, Maki BE, Rogers SA, Schoenen F, Seed PC. Goller CC, et al. Among authors: tower na. PLoS One. 2014 Jul 1;9(7):e96054. doi: 10.1371/journal.pone.0096054. eCollection 2014. PLoS One. 2014. PMID: 24983234 Free PMC article.
Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.
Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, Julander JG, Smith JM, Filone CM, Connor JH, Sakurai Y, Davey RA. Chung DH, et al. Among authors: tower na. PLoS Pathog. 2014 Jun 26;10(6):e1004213. doi: 10.1371/journal.ppat.1004213. eCollection 2014 Jun. PLoS Pathog. 2014. PMID: 24967809 Free PMC article.
ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV).
Chung D, Schroeder CE, Sotsky J, Yao T, Roy S, Smith RA, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, White EL, Aubé J, Golden JE. Chung D, et al. Among authors: tower na. 2012 Dec 17 [updated 2013 Nov 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 17 [updated 2013 Nov 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24479198 Free Books & Documents. Review.
19 results