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What we know but do not understand about nidovirus helicases.
Lehmann KC, Snijder EJ, Posthuma CC, Gorbalenya AE. Lehmann KC, et al. Among authors: posthuma cc. Virus Res. 2015 Apr 16;202:12-32. doi: 10.1016/j.virusres.2014.12.001. Epub 2014 Dec 8. Virus Res. 2015. PMID: 25497126 Free PMC article. Review.
Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase.
Deng Z, Lehmann KC, Li X, Feng C, Wang G, Zhang Q, Qi X, Yu L, Zhang X, Feng W, Wu W, Gong P, Tao Y, Posthuma CC, Snijder EJ, Gorbalenya AE, Chen Z. Deng Z, et al. Among authors: posthuma cc. Nucleic Acids Res. 2014 Mar;42(5):3464-77. doi: 10.1093/nar/gkt1310. Epub 2013 Dec 24. Nucleic Acids Res. 2014. PMID: 24369429 Free PMC article.
Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses.
Lehmann KC, Gulyaeva A, Zevenhoven-Dobbe JC, Janssen GM, Ruben M, Overkleeft HS, van Veelen PA, Samborskiy DV, Kravchenko AA, Leontovich AM, Sidorov IA, Snijder EJ, Posthuma CC, Gorbalenya AE. Lehmann KC, et al. Among authors: posthuma cc. Nucleic Acids Res. 2015 Sep 30;43(17):8416-34. doi: 10.1093/nar/gkv838. Epub 2015 Aug 24. Nucleic Acids Res. 2015. PMID: 26304538 Free PMC article.
Cyclophilins and cyclophilin inhibitors in nidovirus replication.
de Wilde AH, Pham U, Posthuma CC, Snijder EJ. de Wilde AH, et al. Among authors: posthuma cc. Virology. 2018 Sep;522:46-55. doi: 10.1016/j.virol.2018.06.011. Epub 2018 Jul 12. Virology. 2018. PMID: 30014857 Free PMC article. Review.
33 results