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Abuse Potential and Pharmacodynamic Characteristics of Oral and Intranasal Eluxadoline, a Mixed μ- and κ-Opioid Receptor Agonist and δ-Opioid Receptor Antagonist.
Levy-Cooperman N, McIntyre G, Bonifacio L, McDonnell M, Davenport JM, Covington PS, Dove LS, Sellers EM. Levy-Cooperman N, et al. Among authors: mcintyre g. J Pharmacol Exp Ther. 2016 Dec;359(3):471-481. doi: 10.1124/jpet.116.236547. Epub 2016 Sep 19. J Pharmacol Exp Ther. 2016. PMID: 27647873 Free PMC article. Clinical Trial.
Eluxadoline for Irritable Bowel Syndrome with Diarrhea.
Lembo AJ, Lacy BE, Zuckerman MJ, Schey R, Dove LS, Andrae DA, Davenport JM, McIntyre G, Lopez R, Turner L, Covington PS. Lembo AJ, et al. Among authors: mcintyre g. N Engl J Med. 2016 Jan 21;374(3):242-53. doi: 10.1056/NEJMoa1505180. N Engl J Med. 2016. PMID: 26789872 Free article. Clinical Trial.
Evaluation of Eluxadoline Effect on Cardiac Repolarization.
Bonifacio L, Hunt TL, McIntyre G, Dove LS, Covington PS. Bonifacio L, et al. Among authors: mcintyre g. Clin Pharmacol Drug Dev. 2018 Sep;7(7):727-736. doi: 10.1002/cpdd.453. Epub 2018 Apr 16. Clin Pharmacol Drug Dev. 2018. PMID: 29659201 Free PMC article. Clinical Trial.
Randomized, double-blind, phase II, multicenter study evaluating the safety/tolerability and efficacy of JNJ-Q2, a novel fluoroquinolone, compared with linezolid for treatment of acute bacterial skin and skin structure infection.
Covington P, Davenport JM, Andrae D, O'Riordan W, Liverman L, McIntyre G, Almenoff J. Covington P, et al. Among authors: mcintyre g. Antimicrob Agents Chemother. 2011 Dec;55(12):5790-7. doi: 10.1128/AAC.05044-11. Epub 2011 Sep 26. Antimicrob Agents Chemother. 2011. PMID: 21947389 Free PMC article. Clinical Trial.
295 results