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Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A. Di Gennaro E, et al. Among authors: budillon a. J Cell Physiol. 2003 Apr;195(1):139-50. doi: 10.1002/jcp.10239. J Cell Physiol. 2003. PMID: 12599217
R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation.
Caraglia M, Marra M, Leonetti C, Meo G, D'Alessandro AM, Baldi A, Santini D, Tonini G, Bertieri R, Zupi G, Budillon A, Abbruzzese A. Caraglia M, et al. Among authors: budillon a. J Cell Physiol. 2007 May;211(2):533-43. doi: 10.1002/jcp.20960. J Cell Physiol. 2007. PMID: 17192846
The clinical response on bone metastasis from breast and lung cancer during treatment with zoledronic acid is inversely correlated to skeletal related events (SRE).
Facchini G, Caraglia M, Santini D, Nasti G, Ottaiano A, Striano S, Maiolino P, Ruberto M, Fiore F, Tonini G, Budillon A, Iaffaioli RV, Zeppetella GL. Facchini G, et al. Among authors: budillon a. J Exp Clin Cancer Res. 2007 Sep;26(3):307-12. J Exp Clin Cancer Res. 2007. PMID: 17987788 Clinical Trial.
224 results