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Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegeneration.
Synofzik M, Haack TB, Kopajtich R, Gorza M, Rapaport D, Greiner M, Schönfeld C, Freiberg C, Schorr S, Holl RW, Gonzalez MA, Fritsche A, Fallier-Becker P, Zimmermann R, Strom TM, Meitinger T, Züchner S, Schüle R, Schöls L, Prokisch H. Synofzik M, et al. Among authors: zimmermann r. Am J Hum Genet. 2014 Dec 4;95(6):689-97. doi: 10.1016/j.ajhg.2014.10.013. Epub 2014 Nov 20. Am J Hum Genet. 2014. PMID: 25466870 Free PMC article.
Functions and pathologies of BiP and its interaction partners.
Dudek J, Benedix J, Cappel S, Greiner M, Jalal C, Müller L, Zimmermann R. Dudek J, et al. Among authors: zimmermann r. Cell Mol Life Sci. 2009 May;66(9):1556-69. doi: 10.1007/s00018-009-8745-y. Cell Mol Life Sci. 2009. PMID: 19151922 Free PMC article. Review.
Evolutionary gain of function for the ER membrane protein Sec62 from yeast to humans.
Müller L, de Escauriaza MD, Lajoie P, Theis M, Jung M, Müller A, Burgard C, Greiner M, Snapp EL, Dudek J, Zimmermann R. Müller L, et al. Among authors: zimmermann r. Mol Biol Cell. 2010 Mar 1;21(5):691-703. doi: 10.1091/mbc.e09-08-0730. Epub 2010 Jan 13. Mol Biol Cell. 2010. PMID: 20071467 Free PMC article.
BiP modulates the affinity of its co-chaperone ERj1 for ribosomes.
Benedix J, Lajoie P, Jaiswal H, Burgard C, Greiner M, Zimmermann R, Rospert S, Snapp EL, Dudek J. Benedix J, et al. Among authors: zimmermann r. J Biol Chem. 2010 Nov 19;285(47):36427-33. doi: 10.1074/jbc.M110.143263. Epub 2010 Sep 23. J Biol Chem. 2010. PMID: 20864538 Free PMC article.
Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.
Lang S, Benedix J, Fedeles SV, Schorr S, Schirra C, Schäuble N, Jalal C, Greiner M, Hassdenteufel S, Tatzelt J, Kreutzer B, Edelmann L, Krause E, Rettig J, Somlo S, Zimmermann R, Dudek J. Lang S, et al. Among authors: zimmermann r. J Cell Sci. 2012 Apr 15;125(Pt 8):1958-69. doi: 10.1242/jcs.096727. Epub 2012 Feb 28. J Cell Sci. 2012. PMID: 22375059 Free PMC article.
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER.
Schäuble N, Lang S, Jung M, Cappel S, Schorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton AW, Paton JC, Cavalié A, Zimmermann R. Schäuble N, et al. Among authors: zimmermann r. EMBO J. 2012 Aug 1;31(15):3282-96. doi: 10.1038/emboj.2012.189. Epub 2012 Jul 13. EMBO J. 2012. PMID: 22796945 Free PMC article.
CK2 phosphorylation of human Sec63 regulates its interaction with Sec62.
Ampofo E, Welker S, Jung M, Müller L, Greiner M, Zimmermann R, Montenarh M. Ampofo E, et al. Among authors: zimmermann r. Biochim Biophys Acta. 2013 Apr;1830(4):2938-45. doi: 10.1016/j.bbagen.2012.12.020. Epub 2012 Dec 31. Biochim Biophys Acta. 2013. PMID: 23287549
2,056 results