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Mnks, eIF4E phosphorylation and cancer.
Proud CG. Proud CG. Biochim Biophys Acta. 2015 Jul;1849(7):766-73. doi: 10.1016/j.bbagrm.2014.10.003. Epub 2014 Oct 23. Biochim Biophys Acta. 2015. PMID: 25450520 Review.
Targeting Mnks for cancer therapy.
Hou J, Lam F, Proud C, Wang S. Hou J, et al. Oncotarget. 2012 Feb;3(2):118-31. doi: 10.18632/oncotarget.453. Oncotarget. 2012. PMID: 22392765 Free PMC article. Review.
The MAP kinase-interacting kinases (MNKs) as targets in oncology.
Xie J, Merrett JE, Jensen KB, Proud CG. Xie J, et al. Among authors: proud cg. Expert Opin Ther Targets. 2019 Mar;23(3):187-199. doi: 10.1080/14728222.2019.1571043. Epub 2019 Jan 24. Expert Opin Ther Targets. 2019. PMID: 30650992 Review.
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
Knight JRP, Alexandrou C, Skalka GL, Vlahov N, Pennel K, Officer L, Teodosio A, Kanellos G, Gay DM, May-Wilson S, Smith EM, Najumudeen AK, Gilroy K, Ridgway RA, Flanagan DJ, Smith RCL, McDonald L, MacKay C, Cheasty A, McArthur K, Stanway E, Leach JD, Jackstadt R, Waldron JA, Campbell AD, Vlachogiannis G, Valeri N, Haigis KM, Sonenberg N, Proud CG, Jones NP, Swarbrick ME, McKinnon HJ, Faller WJ, Le Quesne J, Edwards J, Willis AE, Bushell M, Sansom OJ. Knight JRP, et al. Among authors: proud cg. Cancer Discov. 2021 May;11(5):1228-1247. doi: 10.1158/2159-8290.CD-20-0652. Epub 2020 Dec 16. Cancer Discov. 2021. PMID: 33328217 Free PMC article.
341 results