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AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.
Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, Gretzmeier C, Dengjel J, Fimia GM, Piacentini M, Di Bartolomeo S, Velasco G, Cecconi F. Cianfanelli V, et al. Among authors: de zio d, d orazio m. Nat Cell Biol. 2015 Jan;17(1):20-30. doi: 10.1038/ncb3072. Epub 2014 Dec 1. Nat Cell Biol. 2015. PMID: 25438055 Free PMC article.
A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2.
Hangen E, De Zio D, Bordi M, Zhu C, Dessen P, Caffin F, Lachkar S, Perfettini JL, Lazar V, Benard J, Fimia GM, Piacentini M, Harper F, Pierron G, Vicencio JM, Bénit P, de Andrade A, Höglinger G, Culmsee C, Rustin P, Blomgren K, Cecconi F, Kroemer G, Modjtahedi N. Hangen E, et al. Among authors: de andrade a, de zio d. Cell Death Differ. 2010 Jul;17(7):1155-66. doi: 10.1038/cdd.2009.211. Epub 2010 Jan 29. Cell Death Differ. 2010. PMID: 20111043 Free article.
The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage.
De Zio D, Bordi M, Tino E, Lanzuolo C, Ferraro E, Mora E, Ciccosanti F, Fimia GM, Orlando V, Cecconi F. De Zio D, et al. Cell Death Differ. 2011 Mar;18(3):516-27. doi: 10.1038/cdd.2010.125. Epub 2010 Oct 22. Cell Death Differ. 2011. PMID: 20966962 Free PMC article.
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.
D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, Ferri A, Diamantini A, De Zio D, Carrara P, Battistini L, Moreno S, Bacci A, Ammassari-Teule M, Marie H, Cecconi F. D'Amelio M, et al. Among authors: de zio d. Nat Neurosci. 2011 Jan;14(1):69-76. doi: 10.1038/nn.2709. Epub 2010 Dec 12. Nat Neurosci. 2011. PMID: 21151119
Apaf1 plays a pro-survival role by regulating centrosome morphology and function.
Ferraro E, Pesaresi MG, De Zio D, Cencioni MT, Gortat A, Cozzolino M, Berghella L, Salvatore AM, Oettinghaus B, Scorrano L, Pérez-Payà E, Cecconi F. Ferraro E, et al. Among authors: de zio d. J Cell Sci. 2011 Oct 15;124(Pt 20):3450-63. doi: 10.1242/jcs.086298. Epub 2011 Oct 7. J Cell Sci. 2011. PMID: 21984814 Free article.
New insights into the link between DNA damage and apoptosis.
De Zio D, Cianfanelli V, Cecconi F. De Zio D, et al. Antioxid Redox Signal. 2013 Aug 20;19(6):559-71. doi: 10.1089/ars.2012.4938. Epub 2012 Nov 9. Antioxid Redox Signal. 2013. PMID: 23025416 Free PMC article. Review.
38 results