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Targeting the DNA repair pathway in Ewing sarcoma.
Stewart E, Goshorn R, Bradley C, Griffiths LM, Benavente C, Twarog NR, Miller GM, Caufield W, Freeman BB 3rd, Bahrami A, Pappo A, Wu J, Loh A, Karlström Å, Calabrese C, Gordon B, Tsurkan L, Hatfield MJ, Potter PM, Snyder SE, Thiagarajan S, Shirinifard A, Sablauer A, Shelat AA, Dyer MA. Stewart E, et al. Among authors: hatfield mj. Cell Rep. 2014 Nov 6;9(3):829-41. doi: 10.1016/j.celrep.2014.09.028. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437539 Free PMC article.
Carboxylesterase inhibitors.
Hatfield MJ, Potter PM. Hatfield MJ, et al. Expert Opin Ther Pat. 2011 Aug;21(8):1159-71. doi: 10.1517/13543776.2011.586339. Epub 2011 May 24. Expert Opin Ther Pat. 2011. PMID: 21609191 Free PMC article. Review.
Targeting ALK in pediatric RMS does not induce antitumor activity in vivo.
Wierdl M, Tsurkan L, Chi L, Hatfield MJ, Tollemar V, Bradley C, Chen X, Qu C, Potter PM. Wierdl M, et al. Among authors: hatfield mj. Cancer Chemother Pharmacol. 2018 Aug;82(2):251-263. doi: 10.1007/s00280-018-3615-7. Epub 2018 May 31. Cancer Chemother Pharmacol. 2018. PMID: 29855693 Free PMC article.
An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11.
Wierdl M, Tsurkan L, Hyatt JL, Edwards CC, Hatfield MJ, Morton CL, Houghton PJ, Danks MK, Redinbo MR, Potter PM. Wierdl M, et al. Among authors: hatfield mj. Cancer Gene Ther. 2008 Mar;15(3):183-92. doi: 10.1038/sj.cgt.7701112. Epub 2008 Jan 11. Cancer Gene Ther. 2008. PMID: 18188187
Carboxylesterases: General detoxifying enzymes.
Hatfield MJ, Umans RA, Hyatt JL, Edwards CC, Wierdl M, Tsurkan L, Taylor MR, Potter PM. Hatfield MJ, et al. Chem Biol Interact. 2016 Nov 25;259(Pt B):327-331. doi: 10.1016/j.cbi.2016.02.011. Epub 2016 Feb 15. Chem Biol Interact. 2016. PMID: 26892220 Free PMC article. Review.
25 results