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Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, Oshimura M, Ishigaki Y, Hamasaki K, Kodama Y, Yuasa S, Fukuda K, Hirashima K, Seimiya H, Koyama H, Shimizu T, Takemoto M, Yokote K, Goto M, Tahara H. Shimamoto A, et al. PLoS One. 2014 Nov 12;9(11):e112900. doi: 10.1371/journal.pone.0112900. eCollection 2014. PLoS One. 2014. PMID: 25390333 Free PMC article.
Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome.
Kato H, Maezawa Y, Ouchi Y, Takayama N, Sone M, Sone K, Takada-Watanabe A, Tsujimura K, Koshizaka M, Nagasawa S, Saitoh H, Ohtaka M, Nakanishi M, Tahara H, Shimamoto A, Iwama A, Eto K, Yokote K. Kato H, et al. Among authors: shimamoto a. Stem Cell Res. 2021 May;53:102360. doi: 10.1016/j.scr.2021.102360. Epub 2021 Apr 23. Stem Cell Res. 2021. PMID: 34087989 Free article.
miR-22 represses cancer progression by inducing cellular senescence.
Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, Tamaki A, Matsunaga J, Takahashi RU, Takata T, Shimamoto A, Ochiya T, Tahara H. Xu D, et al. Among authors: shimamoto a. J Cell Biol. 2011 Apr 18;193(2):409-24. doi: 10.1083/jcb.201010100. J Cell Biol. 2011. PMID: 21502362 Free PMC article.
TERT attenuated ER stress-induced cell death.
Hosoi T, Inoue Y, Nakatsu K, Matsushima N, Kiyose N, Shimamoto A, Tahara H, Ozawa K. Hosoi T, et al. Among authors: shimamoto a. Biochem Biophys Res Commun. 2014 May 2;447(2):378-82. doi: 10.1016/j.bbrc.2014.04.034. Epub 2014 Apr 16. Biochem Biophys Res Commun. 2014. PMID: 24746472
Telomere G-tail Length is a Promising Biomarker Related to White Matter Lesions and Endothelial Dysfunction in Patients With Cardiovascular Risk: A Cross-sectional Study.
Nezu T, Hosomi N, Takahashi T, Anno K, Aoki S, Shimamoto A, Maruyama H, Hayashi T, Matsumoto M, Tahara H. Nezu T, et al. Among authors: shimamoto a. EBioMedicine. 2015 May 30;2(8):960-7. doi: 10.1016/j.ebiom.2015.05.025. eCollection 2015 Aug. EBioMedicine. 2015. PMID: 26425704 Free PMC article.
158 results