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Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, Oshimura M, Ishigaki Y, Hamasaki K, Kodama Y, Yuasa S, Fukuda K, Hirashima K, Seimiya H, Koyama H, Shimizu T, Takemoto M, Yokote K, Goto M, Tahara H. Shimamoto A, et al. Among authors: hirashima k. PLoS One. 2014 Nov 12;9(11):e112900. doi: 10.1371/journal.pone.0112900. eCollection 2014. PLoS One. 2014. PMID: 25390333 Free PMC article.
Telomere length influences cancer cell differentiation in vivo.
Hirashima K, Migita T, Sato S, Muramatsu Y, Ishikawa Y, Seimiya H. Hirashima K, et al. Mol Cell Biol. 2013 Aug;33(15):2988-95. doi: 10.1128/MCB.00136-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716593 Free PMC article.
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.
Deardorff MA, Bando M, Nakato R, Watrin E, Itoh T, Minamino M, Saitoh K, Komata M, Katou Y, Clark D, Cole KE, De Baere E, Decroos C, Di Donato N, Ernst S, Francey LJ, Gyftodimou Y, Hirashima K, Hullings M, Ishikawa Y, Jaulin C, Kaur M, Kiyono T, Lombardi PM, Magnaghi-Jaulin L, Mortier GR, Nozaki N, Petersen MB, Seimiya H, Siu VM, Suzuki Y, Takagaki K, Wilde JJ, Willems PJ, Prigent C, Gillessen-Kaesbach G, Christianson DW, Kaiser FJ, Jackson LG, Hirota T, Krantz ID, Shirahige K. Deardorff MA, et al. Among authors: hirashima k. Nature. 2012 Sep 13;489(7415):313-7. doi: 10.1038/nature11316. Nature. 2012. PMID: 22885700 Free PMC article.
[A follow-up survey of change in activities, including physical, cognitive, and mental functions, after the voluntary return of driver's license in Tokushima community-dwelling older adults].
Hirashima K, Higuchi Y, Yanagisawa Y, Uguisu H, Shibuya M. Hirashima K, et al. Nihon Koshu Eisei Zasshi. 2022 Jan 28;69(1):59-66. doi: 10.11236/jph.21-030. Epub 2021 Dec 10. Nihon Koshu Eisei Zasshi. 2022. PMID: 34759171 Free article. Japanese. No abstract available.
The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.
Sato M, Kadomatsu T, Miyata K, Warren JS, Tian Z, Zhu S, Horiguchi H, Makaju A, Bakhtina A, Morinaga J, Sugizaki T, Hirashima K, Yoshinobu K, Imasaka M, Araki M, Komohara Y, Wakayama T, Nakagawa S, Franklin S, Node K, Araki K, Oike Y. Sato M, et al. Among authors: hirashima k. Nat Commun. 2021 May 5;12(1):2529. doi: 10.1038/s41467-021-22735-7. Nat Commun. 2021. PMID: 33953175 Free PMC article.
246 results