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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord ENJ, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, Rogatti S, Hartley RC, Eaton S, Costa ASH, Brookes PS, Davidson SM, Duchen MR, Saeb-Parsy K, Shattock MJ, Robinson AJ, Work LM, Frezza C, Krieg T, Murphy MP. Chouchani ET, et al. Among authors: nadtochiy sm. Nature. 2014 Nov 20;515(7527):431-435. doi: 10.1038/nature13909. Epub 2014 Nov 5. Nature. 2014. PMID: 25383517 Free PMC article.
Direct evidence for S-nitrosation of mitochondrial complex I.
Burwell LS, Nadtochiy SM, Tompkins AJ, Young S, Brookes PS. Burwell LS, et al. Among authors: nadtochiy sm. Biochem J. 2006 Mar 15;394(Pt 3):627-34. doi: 10.1042/BJ20051435. Biochem J. 2006. PMID: 16371007 Free PMC article.
Cardioprotection by metabolic shut-down and gradual wake-up.
Burwell LS, Nadtochiy SM, Brookes PS. Burwell LS, et al. Among authors: nadtochiy sm. J Mol Cell Cardiol. 2009 Jun;46(6):804-10. doi: 10.1016/j.yjmcc.2009.02.026. Epub 2009 Mar 10. J Mol Cell Cardiol. 2009. PMID: 19285082 Free PMC article. Review.
In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine.
Nadtochiy SM, Burwell LS, Ingraham CA, Spencer CM, Friedman AE, Pinkert CA, Brookes PS. Nadtochiy SM, et al. J Mol Cell Cardiol. 2009 Jun;46(6):960-8. doi: 10.1016/j.yjmcc.2009.01.012. Epub 2009 Feb 3. J Mol Cell Cardiol. 2009. PMID: 19339206 Free PMC article.
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.
Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RA, Murphy MP. Prime TA, et al. Among authors: nadtochiy sm. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10764-9. doi: 10.1073/pnas.0903250106. Epub 2009 Jun 15. Proc Natl Acad Sci U S A. 2009. PMID: 19528654 Free PMC article.
50 results