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An in vivo model of human small intestine using pluripotent stem cells.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA. Watson CL, et al. Among authors: mayhew cn. Nat Med. 2014 Nov;20(11):1310-4. doi: 10.1038/nm.3737. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326803 Free PMC article.
In vitro generation of human pluripotent stem cell derived lung organoids.
Dye BR, Hill DR, Ferguson MA, Tsai YH, Nagy MS, Dyal R, Wells JM, Mayhew CN, Nattiv R, Klein OD, White ES, Deutsch GH, Spence JR. Dye BR, et al. Among authors: mayhew cn. Elife. 2015 Mar 24;4:e05098. doi: 10.7554/eLife.05098. Elife. 2015. PMID: 25803487 Free PMC article.
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.
Ouchi R, Togo S, Kimura M, Shinozawa T, Koido M, Koike H, Thompson W, Karns RA, Mayhew CN, McGrath PS, McCauley HA, Zhang RR, Lewis K, Hakozaki S, Ferguson A, Saiki N, Yoneyama Y, Takeuchi I, Mabuchi Y, Akazawa C, Yoshikawa HY, Wells JM, Takebe T. Ouchi R, et al. Among authors: mayhew cn. Cell Metab. 2019 Aug 6;30(2):374-384.e6. doi: 10.1016/j.cmet.2019.05.007. Epub 2019 May 30. Cell Metab. 2019. PMID: 31155493 Free PMC article.
High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.
Chlon TM, Hoskins EE, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: mayhew cn. J Virol. 2014 Oct;88(19):11315-26. doi: 10.1128/JVI.01533-14. Epub 2014 Jul 16. J Virol. 2014. PMID: 25031356 Free PMC article.
Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage.
Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: mayhew cn. Stem Cell Reports. 2016 Jan 12;6(1):44-54. doi: 10.1016/j.stemcr.2015.12.001. Stem Cell Reports. 2016. PMID: 26771352 Free PMC article.
59 results