Yang X - Search Results

1

Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.

Chen D, Shen A, Li J, Shi F, Chen W, Ren J, Liu H, Xu Y, Wang X, Yang X, Sun Y, Yang M, He J, Wang Y, Zhang L, Huang M, Geng M, Xiong B, Shen J. Chen D, et al. Among authors: yang m, yang x. Eur J Med Chem. 2014 Nov 24;87:765-81. doi: 10.1016/j.ejmech.2014.09.065. Epub 2014 Sep 22. Eur J Med Chem. 2014. PMID: 25313505

2

Discovery of novel 2,4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases.

Song Z, Yang Y, Liu Z, Peng X, Guo J, Yang X, Wu K, Ai J, Ding J, Geng M, Zhang A. Song Z, et al. Among authors: yang x, yang y. J Med Chem. 2015 Jan 8;58(1):197-211. doi: 10.1021/jm5005144. Epub 2014 May 8. J Med Chem. 2015. PMID: 24785465

3

Design, synthesis and preliminary bioactivity studies of 2-thioxo-4-thiazolidinone derivatives as Bcl-2 inhibitors.

Wan Y, Wu S, Xiao G, Liu T, Hou X, Chen C, Guan P, Yang X, Fang H. Wan Y, et al. Among authors: yang x. Bioorg Med Chem. 2015 May 1;23(9):1994-2003. doi: 10.1016/j.bmc.2015.03.024. Epub 2015 Mar 14. Bioorg Med Chem. 2015. PMID: 25818766

4

c-Myc alterations confer therapeutic response and acquired resistance to c-Met inhibitors in MET-addicted cancers.

Shen A, Wang L, Huang M, Sun J, Chen Y, Shen YY, Yang X, Wang X, Ding J, Geng M. Shen A, et al. Among authors: yang x. Cancer Res. 2015 Nov 1;75(21):4548-59. doi: 10.1158/0008-5472.CAN-14-2743. Epub 2015 Oct 19. Cancer Res. 2015. PMID: 26483207

5

Discovery of 3-(5'-Substituted)-Benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors: Design, Synthesis, and Biological Evaluation.

Yan W, Wang X, Dai Y, Zhao B, Yang X, Fan J, Gao Y, Meng F, Wang Y, Luo C, Ai J, Geng M, Duan W. Yan W, et al. Among authors: yang x. J Med Chem. 2016 Jul 28;59(14):6690-708. doi: 10.1021/acs.jmedchem.6b00056. Epub 2016 Jul 6. J Med Chem. 2016. PMID: 27348537

6

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer.

Zeng H, Qu J, Jin N, Xu J, Lin C, Chen Y, Yang X, He X, Tang S, Lan X, Yang X, Chen Z, Huang M, Ding J, Geng M. Zeng H, et al. Among authors: yang x. Cancer Cell. 2016 Sep 12;30(3):459-473. doi: 10.1016/j.ccell.2016.08.001. Cancer Cell. 2016. PMID: 27622335 Free article.

7

Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.

Yuan B, Ye N, Song SS, Wang YT, Song Z, Chen HD, Chen CH, Huan XJ, Wang YQ, Su Y, Shen YY, Sun YM, Yang XY, Chen Y, Guo SY, Gan Y, Gao ZW, Chen XY, Ding J, He JX, Zhang A, Miao ZH. Yuan B, et al. Cancer Lett. 2017 Feb 1;386:47-56. doi: 10.1016/j.canlet.2016.11.010. Epub 2016 Nov 12. Cancer Lett. 2017. PMID: 27847302

8

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution.

He JX, Wang M, Huan XJ, Chen CH, Song SS, Wang YQ, Liao XM, Tan C, He Q, Tong LJ, Wang YT, Li XH, Su Y, Shen YY, Sun YM, Yang XY, Chen Y, Gao ZW, Chen XY, Xiong B, Lu XL, Ding J, Yang CH, Miao ZH. He JX, et al. Oncotarget. 2017 Jan 17;8(3):4156-4168. doi: 10.18632/oncotarget.13749. Oncotarget. 2017. PMID: 27926532 Free PMC article.

9

Polymeric immunoglobulin receptor promotes tumor growth in hepatocellular carcinoma.

Yue X, Ai J, Xu Y, Chen Y, Huang M, Yang X, Hu B, Zhang H, He C, Yang X, Tang W, Peng X, Dong L, Wang H, Fan J, Ding J, Geng M. Yue X, et al. Among authors: yang x. Hepatology. 2017 Jun;65(6):1948-1962. doi: 10.1002/hep.29036. Epub 2017 Apr 28. Hepatology. 2017. PMID: 28073159

10

Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors.

Chen C, Hou X, Wang G, Pan W, Yang X, Zhang Y, Fang H. Chen C, et al. Among authors: yang x. Eur J Med Chem. 2017 Jun 16;133:11-23. doi: 10.1016/j.ejmech.2017.03.064. Epub 2017 Mar 28. Eur J Med Chem. 2017. PMID: 28371677

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