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Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors.
Dražić T, Molčanov K, Sachdev V, Malnar M, Hećimović S, Patankar JV, Obrowsky S, Levak-Frank S, Habuš I, Kratky D. Dražić T, et al. Among authors: kratky d. Eur J Med Chem. 2014 Nov 24;87:722-34. doi: 10.1016/j.ejmech.2014.10.014. Epub 2014 Oct 7. Eur J Med Chem. 2014. PMID: 25305716 Free PMC article.
The role of lipoprotein lipase in adipose tissue development and metabolism.
Zechner R, Strauss J, Frank S, Wagner E, Hofmann W, Kratky D, Hiden M, Levak-Frank S. Zechner R, et al. Among authors: kratky d. Int J Obes Relat Metab Disord. 2000 Nov;24 Suppl 4:S53-6. doi: 10.1038/sj.ijo.0801506. Int J Obes Relat Metab Disord. 2000. PMID: 11126243 Review.
Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity.
Strauss JG, Zimmermann R, Hrzenjak A, Zhou Y, Kratky D, Levak-Frank S, Kostner GM, Zechner R, Frank S. Strauss JG, et al. Among authors: kratky d. Biochem J. 2002 Nov 15;368(Pt 1):69-79. doi: 10.1042/BJ20020306. Biochem J. 2002. PMID: 12164779 Free PMC article.
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, Kratky D. Kratzer A, et al. Among authors: kratky d. J Lipid Res. 2009 Feb;50(2):312-26. doi: 10.1194/jlr.M800376-JLR200. Epub 2008 Sep 23. J Lipid Res. 2009. PMID: 18812595 Free PMC article.
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: kratky d. J Biol Chem. 2010 Jun 25;285(26):20192-201. doi: 10.1074/jbc.M110.107854. Epub 2010 Apr 27. J Biol Chem. 2010. PMID: 20424161 Free PMC article.
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.
Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Fröhlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D. Buchebner M, et al. Among authors: kratky d. J Lipid Res. 2010 Oct;51(10):2896-908. doi: 10.1194/jlr.M004259. Epub 2010 Jul 12. J Lipid Res. 2010. PMID: 20625037 Free PMC article.
Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.
Patankar JV, Chandak PG, Obrowsky S, Pfeifer T, Diwoky C, Uellen A, Sattler W, Stollberger R, Hoefler G, Heinemann A, Battle M, Duncan S, Kratky D, Levak-Frank S. Patankar JV, et al. Among authors: kratky d. Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E478-88. doi: 10.1152/ajpendo.00457.2010. Epub 2010 Dec 21. Am J Physiol Endocrinol Metab. 2011. PMID: 21177287 Free PMC article.
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
Aflaki E, Radovic B, Chandak PG, Kolb D, Eisenberg T, Ring J, Fertschai I, Uellen A, Wolinski H, Kohlwein SD, Zechner R, Levak-Frank S, Sattler W, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: kratky d. J Biol Chem. 2011 Mar 4;286(9):7418-28. doi: 10.1074/jbc.M110.175703. Epub 2011 Jan 1. J Biol Chem. 2011. PMID: 21196579 Free PMC article.
117 results