Gillespie W - Search Results

1

Modeling and simulation for medical product development and evaluation: highlights from the FDA-C-Path-ISOP 2013 workshop.

Romero K, Sinha V, Allerheiligen S, Danhof M, Pinheiro J, Kruhlak N, Wang Y, Wang SJ, Sauer JM, Marier JF, Corrigan B, Rogers J, Lambers Heerspink HJ, Gumbo T, Vis P, Watkins P, Morrison T, Gillespie W, Gordon MF, Stephenson D, Hanna D, Pfister M, Lalonde R, Colatsky T. Romero K, et al. Among authors: gillespie w. J Pharmacokinet Pharmacodyn. 2014 Dec;41(6):545-52. doi: 10.1007/s10928-014-9390-0. Epub 2014 Oct 7. J Pharmacokinet Pharmacodyn. 2014. PMID: 25288257

2

Pharmacometrics as a discipline is entering the "industrialization" phase: standards, automation, knowledge sharing, and training are critical for future success.

Romero K, Corrigan B, Tornoe CW, Gobburu JV, Danhof M, Gillespie WR, Gastonguay MR, Meibohm B, Derendorf H. Romero K, et al. Among authors: gillespie wr. J Clin Pharmacol. 2010 Sep;50(9 Suppl):9S-19S. doi: 10.1177/0091270010377788. J Clin Pharmacol. 2010. PMID: 20881213 No abstract available.

3

Combining patient-level and summary-level data for Alzheimer's disease modeling and simulation: a β regression meta-analysis.

Rogers JA, Polhamus D, Gillespie WR, Ito K, Romero K, Qiu R, Stephenson D, Gastonguay MR, Corrigan B. Rogers JA, et al. J Pharmacokinet Pharmacodyn. 2012 Oct;39(5):479-98. doi: 10.1007/s10928-012-9263-3. Epub 2012 Jul 21. J Pharmacokinet Pharmacodyn. 2012. PMID: 22821139

4

A model of fracture risk used to examine the link between bone mineral density and the impact of different therapeutic mechanisms on fracture outcomes in patients with osteoporosis.

Eudy-Byrne RJ, Gillespie W, Riggs MM, Gastonguay MR. Eudy-Byrne RJ, et al. Among authors: gillespie w. J Pharmacokinet Pharmacodyn. 2017 Dec;44(6):599-609. doi: 10.1007/s10928-017-9551-z. Epub 2017 Oct 28. J Pharmacokinet Pharmacodyn. 2017. PMID: 29081020

5

Commentary on "Physiologically based pharmacokinetic modeling as a tool for drug development".

Ludden TM, Gillespie WR, Bachman WJ. Ludden TM, et al. Among authors: gillespie wr. J Pharmacokinet Biopharm. 1995 Apr;23(2):231-5. doi: 10.1007/BF02354274. J Pharmacokinet Biopharm. 1995. PMID: 8719239 No abstract available.

6

Exposure-response modelling for empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in patients with type 2 diabetes.

Riggs MM, Seman LJ, Staab A, MacGregor TR, Gillespie W, Gastonguay MR, Woerle HJ, Macha S. Riggs MM, et al. Among authors: gillespie w. Br J Clin Pharmacol. 2014 Dec;78(6):1407-18. doi: 10.1111/bcp.12453. Br J Clin Pharmacol. 2014. PMID: 24964723 Free PMC article.

7

Facilitating pharmacometric workflow with the metrumrg package for R.

Bergsma TT, Knebel W, Fisher J, Gillespie WR, Riggs MM, Gibiansky L, Gastonguay MR. Bergsma TT, et al. Among authors: gillespie wr. Comput Methods Programs Biomed. 2013 Jan;109(1):77-85. doi: 10.1016/j.cmpb.2012.08.009. Epub 2012 Sep 29. Comput Methods Programs Biomed. 2013. PMID: 23026560

8

Noncompartmental versus compartmental modelling in clinical pharmacokinetics.

Gillespie WR. Gillespie WR. Clin Pharmacokinet. 1991 Apr;20(4):253-62. doi: 10.2165/00003088-199120040-00001. Clin Pharmacokinet. 1991. PMID: 2036746 Review. No abstract available.

9

A note on appropriate constraints on the initial input response when applying deconvolution.

Veng-Pedersen P, Gillespie WR. Veng-Pedersen P, et al. Among authors: gillespie wr. J Pharmacokinet Biopharm. 1986 Aug;14(4):441-7. doi: 10.1007/BF01059201. J Pharmacokinet Biopharm. 1986. PMID: 3772741

10

Mean residence time in peripheral tissue: a linear disposition parameter useful for evaluating a drug's tissue distribution.

Veng-Pedersen P, Gillespie W. Veng-Pedersen P, et al. Among authors: gillespie w. J Pharmacokinet Biopharm. 1984 Oct;12(5):535-43. doi: 10.1007/BF01060131. J Pharmacokinet Biopharm. 1984. PMID: 6520747 No abstract available.

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