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Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing.
Arulanandam R, Batenchuk C, Varette O, Zakaria C, Garcia V, Forbes NE, Davis C, Krishnan R, Karmacharya R, Cox J, Sinha A, Babawy A, Waite K, Weinstein E, Falls T, Chen A, Hamill J, De Silva N, Conrad DP, Atkins H, Garson K, Ilkow C, Kærn M, Vanderhyden B, Sonenberg N, Alain T, Le Boeuf F, Bell JC, Diallo JS. Arulanandam R, et al. Among authors: krishnan r. Nat Commun. 2015 Mar 30;6:6410. doi: 10.1038/ncomms7410. Nat Commun. 2015. PMID: 25817275 Free article.
First-in-class small molecule potentiators of cancer virotherapy.
Dornan MH, Krishnan R, Macklin AM, Selman M, El Sayes N, Son HH, Davis C, Chen A, Keillor K, Le PJ, Moi C, Ou P, Pardin C, Canez CR, Le Boeuf F, Bell JC, Smith JC, Diallo JS, Boddy CN. Dornan MH, et al. Among authors: krishnan r. Sci Rep. 2016 May 26;6:26786. doi: 10.1038/srep26786. Sci Rep. 2016. PMID: 27226390 Free PMC article.
Multi-modal Potentiation of Oncolytic Virotherapy by Vanadium Compounds.
Selman M, Rousso C, Bergeron A, Son HH, Krishnan R, El-Sayes NA, Varette O, Chen A, Le Boeuf F, Tzelepis F, Bell JC, Crans DC, Diallo JS. Selman M, et al. Among authors: krishnan r. Mol Ther. 2018 Jan 3;26(1):56-69. doi: 10.1016/j.ymthe.2017.10.014. Epub 2017 Oct 24. Mol Ther. 2018. PMID: 29175158 Free PMC article.
Assessing the Completeness of Reporting in Preclinical Oncolytic Virus Therapy Studies.
Fergusson DA, Wesch NL, Leung GJ, MacNeil JL, Conic I, Presseau J, Cobey KD, Diallo JS, Auer R, Kimmelman J, Kekre N, El-Sayes N, Krishnan R, Keller BA, Ilkow C, Lalu MM. Fergusson DA, et al. Among authors: krishnan r. Mol Ther Oncolytics. 2019 May 21;14:179-187. doi: 10.1016/j.omto.2019.05.004. eCollection 2019 Sep 27. Mol Ther Oncolytics. 2019. PMID: 31276026 Free PMC article.
Targeted gene silencing in the nervous system with CRISPR-Cas13.
Powell JE, Lim CKW, Krishnan R, McCallister TX, Saporito-Magriña C, Zeballos MA, McPheron GD, Gaj T. Powell JE, et al. Among authors: krishnan r. Sci Adv. 2022 Jan 21;8(3):eabk2485. doi: 10.1126/sciadv.abk2485. Epub 2022 Jan 19. Sci Adv. 2022. PMID: 35044815 Free PMC article.
1,080 results