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Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.
Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ. Bharadwaj U, et al. Among authors: dave b. Oncogene. 2015 Mar 12;34(11):1341-53. doi: 10.1038/onc.2014.72. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681959 Free PMC article.
HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway.
Liu Y, Choi DS, Sheng J, Ensor JE, Liang DH, Rodriguez-Aguayo C, Polley A, Benz S, Elemento O, Verma A, Cong Y, Wong H, Qian W, Li Z, Granados-Principal S, Lopez-Berestein G, Landis MD, Rosato RR, Dave B, Wong S, Marchetti D, Sood AK, Chang JC. Liu Y, et al. Among authors: dave b. Stem Cell Reports. 2018 Jan 9;10(1):212-227. doi: 10.1016/j.stemcr.2017.11.010. Epub 2017 Dec 14. Stem Cell Reports. 2018. PMID: 29249663 Free PMC article.
Treatment resistance in stem cells and breast cancer.
Dave B, Chang J. Dave B, et al. J Mammary Gland Biol Neoplasia. 2009 Mar;14(1):79-82. doi: 10.1007/s10911-009-9117-9. Epub 2009 Mar 4. J Mammary Gland Biol Neoplasia. 2009. PMID: 19259795 Review.
Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1.
Choi DS, Blanco E, Kim YS, Rodriguez AA, Zhao H, Huang TH, Chen CL, Jin G, Landis MD, Burey LA, Qian W, Granados SM, Dave B, Wong HH, Ferrari M, Wong ST, Chang JC. Choi DS, et al. Among authors: dave b. Stem Cells. 2014 Sep;32(9):2309-23. doi: 10.1002/stem.1746. Stem Cells. 2014. PMID: 24809620 Free PMC article.
396 results