Bharadwaj U - Search Results

1

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.

Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJ. Bharadwaj U, et al. Cancers (Basel). 2014 Sep 29;6(4):2012-34. doi: 10.3390/cancers6042012. Cancers (Basel). 2014. PMID: 25268166 Free PMC article.

2

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ. Bharadwaj U, et al. Oncogene. 2015 Mar 12;34(11):1341-53. doi: 10.1038/onc.2014.72. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681959 Free PMC article.

3

Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.

Lewis KM, Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Fridley C, Siller R, Tweardy DJ. Lewis KM, et al. Among authors: bharadwaj u. Lung Cancer. 2015 Nov;90(2):182-90. doi: 10.1016/j.lungcan.2015.09.014. Epub 2015 Sep 15. Lung Cancer. 2015. PMID: 26410177 Free PMC article.

4

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species.

Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF. Yuan H, et al. Among authors: bharadwaj u. PLoS One. 2015 Dec 8;10(12):e0143964. doi: 10.1371/journal.pone.0143964. eCollection 2015. PLoS One. 2015. PMID: 26645674 Free PMC article.

5

A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture.

Zheng M, Turton KB, Zhu F, Li Y, Grindle KM, Annis DS, Lu L, Drennan AC, Tweardy DJ, Bharadwaj U, Mosher DF, Rui L. Zheng M, et al. Among authors: bharadwaj u. Oncogenesis. 2016 Jan 4;4(1):e184. doi: 10.1038/oncsis.2015.44. Oncogenesis. 2016. PMID: 26727576 Free PMC article.

6

Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance.

Robinson P, Kasembeli M, Bharadwaj U, Engineer N, Eckols KT, Tweardy DJ. Robinson P, et al. Among authors: bharadwaj u. Biomed Res Int. 2016;2016:1959270. doi: 10.1155/2016/1959270. Epub 2016 Feb 11. Biomed Res Int. 2016. PMID: 26981525 Free PMC article.

7

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.

Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ. Bharadwaj U, et al. Oncotarget. 2016 May 3;7(18):26307-30. doi: 10.18632/oncotarget.8368. Oncotarget. 2016. PMID: 27027445 Free PMC article.

8

STAT3 inhibition prevents lung inflammation, remodeling, and accumulation of Th2 and Th17 cells in a murine asthma model.

Gavino AC, Nahmod K, Bharadwaj U, Makedonas G, Tweardy DJ. Gavino AC, et al. Among authors: bharadwaj u. Allergy. 2016 Dec;71(12):1684-1692. doi: 10.1111/all.12937. Epub 2016 Jun 23. Allergy. 2016. PMID: 27225906

9

Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.

Jung KH, Yoo W, Stevenson HL, Deshpande D, Shen H, Gagea M, Yoo SY, Wang J, Eckols TK, Bharadwaj U, Tweardy DJ, Beretta L. Jung KH, et al. Among authors: bharadwaj u. Clin Cancer Res. 2017 Sep 15;23(18):5537-5546. doi: 10.1158/1078-0432.CCR-16-2253. Epub 2017 May 22. Clin Cancer Res. 2017. PMID: 28533225 Free PMC article.

10

Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.

Singh M, Vianden C, Cantwell MJ, Dai Z, Xiao Z, Sharma M, Khong H, Jaiswal AR, Faak F, Hailemichael Y, Janssen LME, Bharadwaj U, Curran MA, Diab A, Bassett RL, Tweardy DJ, Hwu P, Overwijk WW. Singh M, et al. Among authors: bharadwaj u. Nat Commun. 2017 Nov 13;8(1):1447. doi: 10.1038/s41467-017-01572-7. Nat Commun. 2017. PMID: 29129918 Free PMC article.

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