Sakaki T - Search Results

1

Synthesis and metabolic studies of 1α,2α,25-, 1α,4α,25- and 1α,4β,25-trihydroxyvitamin D3.

Takano M, Sawada D, Yasuda K, Nishikawa M, Takeuchi A, Takagi K, Horie K, Reddy GS, Chen TC, Sakaki T, Kittaka A. Takano M, et al. Among authors: sakaki t. J Steroid Biochem Mol Biol. 2015 Apr;148:34-7. doi: 10.1016/j.jsbmb.2014.09.021. Epub 2014 Sep 26. J Steroid Biochem Mol Biol. 2015. PMID: 25263656 Review.

2

Metabolic studies using recombinant escherichia coli cells producing rat mitochondrial CYP24 CYP24 can convert 1alpha,25-dihydroxyvitamin D3 to calcitroic acid.

Sakaki T, Sawada N, Nonaka Y, Ohyama Y, Inouye K. Sakaki T, et al. Eur J Biochem. 1999 May;262(1):43-8. doi: 10.1046/j.1432-1327.1999.00375.x. Eur J Biochem. 1999. PMID: 10231362 Free article.

Previously we expressed rat 25-hydroxyvitamin D3 24-hydroxylase (CYP24) cDNA in Escherichia coli JM109 and showed that CYP24 catalyses three-step monooxygenation towards 25-hydroxyvitamin D3 and 1alpha,25-dihydroxyvitamin D3 [Akiyoshi-Shibata, M., Sakaki, T., Ohyama …

Previously we expressed rat 25-hydroxyvitamin D3 24-hydroxylase (CYP24) cDNA in Escherichia coli JM109 and showed that CYP24 catalyses three …

3

Metabolism of 20-epimer of 1alpha,25-dihydroxyvitamin D3 by CYP24: species-based difference between humans and rats.

Kusudo T, Sakaki T, Abe D, Fujishima T, Kittaka A, Takayama H, Ohta M, Inouye K. Kusudo T, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2003 Oct 3;309(4):885-92. doi: 10.1016/j.bbrc.2003.08.097. Biochem Biophys Res Commun. 2003. PMID: 13679056

4

C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.

Kamao M, Tatematsu S, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Ozono K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: sakaki t. J Biol Chem. 2004 Apr 16;279(16):15897-907. doi: 10.1074/jbc.M311473200. Epub 2004 Feb 2. J Biol Chem. 2004. PMID: 14757768 Free article.

5

Cell specificity and properties of the C-3 epimerization of Vitamin D3 metabolites.

Kamao M, Tatematsu S, Sawada N, Sakaki T, Hatakeyama S, Kubodera N, Okano T. Kamao M, et al. Among authors: sakaki t. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):39-42. doi: 10.1016/j.jsbmb.2004.03.048. J Steroid Biochem Mol Biol. 2004. PMID: 15225744

6

Metabolism of A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 by CYP24A1.

Kusudo T, Sakaki T, Abe D, Fujishima T, Kittaka A, Takayama H, Hatakeyama S, Ohta M, Inouye K. Kusudo T, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2004 Sep 3;321(4):774-82. doi: 10.1016/j.bbrc.2004.07.040. Biochem Biophys Res Commun. 2004. PMID: 15358094

7

Measurement and characterization of C-3 epimerization activity toward vitamin D3.

Kamao M, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: sakaki t. Arch Biochem Biophys. 2005 Apr 1;436(1):196-205. doi: 10.1016/j.abb.2005.01.017. Arch Biochem Biophys. 2005. PMID: 15752725

8

Metabolism of 2 alpha-propoxy-1 alpha,25-dihydroxyvitamin D3 and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 by human CYP27A1 and CYP24A1.

Abe D, Sakaki T, Kusudo T, Kittaka A, Saito N, Suhara Y, Fujishima T, Takayama H, Hamamoto H, Kamakura M, Ohta M, Inouye K. Abe D, et al. Among authors: sakaki t. Drug Metab Dispos. 2005 Jun;33(6):778-84. doi: 10.1124/dmd.104.003038. Epub 2005 Mar 11. Drug Metab Dispos. 2005. PMID: 15764712

9

Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats.

Hamamoto H, Kusudo T, Urushino N, Masuno H, Yamamoto K, Yamada S, Kamakura M, Ohta M, Inouye K, Sakaki T. Hamamoto H, et al. Among authors: sakaki t. Mol Pharmacol. 2006 Jul;70(1):120-8. doi: 10.1124/mol.106.023275. Epub 2006 Apr 14. Mol Pharmacol. 2006. PMID: 16617161

10

Kinetic studies of 25-hydroxy-19-nor-vitamin D3 and 1 alpha,25-dihydroxy-19-nor-vitamin D3 hydroxylation by CYP27B1 and CYP24A1.

Urushino N, Nakabayashi S, Arai MA, Kittaka A, Chen TC, Yamamoto K, Hayashi K, Kato S, Ohta M, Kamakura M, Ikushiro S, Sakaki T. Urushino N, et al. Among authors: sakaki t. Drug Metab Dispos. 2007 Sep;35(9):1482-8. doi: 10.1124/dmd.107.015602. Epub 2007 Jun 6. Drug Metab Dispos. 2007. PMID: 17553915

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

703 results

Search Page