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African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.
Roses AD, Lutz MW, Saunders AM, Goldgaber D, Saul R, Sundseth SS, Akkari PA, Roses SM, Gottschalk WK, Whitfield KE, Vostrov AA, Hauser MA, Allingham RR, Burns DK, Chiba-Falek O, Welsh-Bohmer KA. Roses AD, et al. Alzheimers Dement. 2014 Nov;10(6):592-601.e2. doi: 10.1016/j.jalz.2014.06.009. Epub 2014 Sep 26. Alzheimers Dement. 2014. PMID: 25260913 Free article.
Age at onset in two common neurodegenerative diseases is genetically controlled.
Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA Jr, Goetz CG, Mastaglia F, Stajich JM, Gibson RA, Middleton LT, Saunders AM, Scott BL, Small GW, Nicodemus KK, Reed AD, Schmechel DE, Welsh-Bohmer KA, Conneally PM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Li YJ, et al. Am J Hum Genet. 2002 Apr;70(4):985-93. doi: 10.1086/339815. Epub 2002 Mar 1. Am J Hum Genet. 2002. PMID: 11875758 Free PMC article.
270 results