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Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes.
Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser PE, Haass C, George-Hyslop PS. Yu G, et al. Among authors: fraser pe. J Biol Chem. 2000 Sep 1;275(35):27348-53. doi: 10.1074/jbc.M002982200. J Biol Chem. 2000. PMID: 10856299 Free article.
alpha-Synuclein membrane interactions and lipid specificity.
Jo E, McLaurin J, Yip CM, St George-Hyslop P, Fraser PE. Jo E, et al. Among authors: fraser pe. J Biol Chem. 2000 Nov 3;275(44):34328-34. doi: 10.1074/jbc.M004345200. J Biol Chem. 2000. PMID: 10915790 Free article.
Cellular membrane composition defines A beta-lipid interactions.
Waschuk SA, Elton EA, Darabie AA, Fraser PE, McLaurin JA. Waschuk SA, et al. Among authors: fraser pe. J Biol Chem. 2001 Sep 7;276(36):33561-8. doi: 10.1074/jbc.M103598200. Epub 2001 Jul 3. J Biol Chem. 2001. PMID: 11438533 Free article.
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins.
Yang DS, Tandon A, Chen F, Yu G, Yu H, Arawaka S, Hasegawa H, Duthie M, Schmidt SD, Ramabhadran TV, Nixon RA, Mathews PM, Gandy SE, Mount HT, St George-Hyslop P, Fraser PE. Yang DS, et al. Among authors: fraser pe. J Biol Chem. 2002 Aug 2;277(31):28135-42. doi: 10.1074/jbc.M110871200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032140 Free article.
Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.
Chen F, Tandon A, Sanjo N, Gu YJ, Hasegawa H, Arawaka S, Lee FJ, Ruan X, Mastrangelo P, Erdebil S, Wang L, Westaway D, Mount HT, Yankner B, Fraser PE, St George-Hyslop P. Chen F, et al. Among authors: fraser pe. J Biol Chem. 2003 May 30;278(22):19974-9. doi: 10.1074/jbc.M210049200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12646573 Free article.
251 results