Theodorescu D - Search Results

1

Discovery and characterization of small molecules that target the GTPase Ral.

Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D. Yan C, et al. Among authors: theodorescu d. Nature. 2014 Nov 20;515(7527):443-7. doi: 10.1038/nature13713. Epub 2014 Sep 14. Nature. 2014. PMID: 25219851 Free PMC article.

2

The role of Ral A in epidermal growth factor receptor-regulated cell motility.

Gildea JJ, Harding MA, Seraj MJ, Gulding KM, Theodorescu D. Gildea JJ, et al. Among authors: theodorescu d. Cancer Res. 2002 Feb 15;62(4):982-5. Cancer Res. 2002. PMID: 11861368

3

Rho proteins in cell migration and metastasis.

Titus B, Schwartz MA, Theodorescu D. Titus B, et al. Among authors: theodorescu d. Crit Rev Eukaryot Gene Expr. 2005;15(2):103-14. doi: 10.1615/critreveukaryotgeneexpr.v15.i2.20. Crit Rev Eukaryot Gene Expr. 2005. PMID: 16022631 Review.

4

RalA and RalB: antagonistic relatives in cancer cell migration.

Oxford G, Owens CR, Titus BJ, Foreman TL, Herlevsen MC, Smith SC, Theodorescu D. Oxford G, et al. Among authors: theodorescu d. Cancer Res. 2005 Aug 15;65(16):7111-20. doi: 10.1158/0008-5472.CAN-04-1957. Cancer Res. 2005. PMID: 16103060

5

The metastasis-associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancer.

Smith SC, Oxford G, Wu Z, Nitz MD, Conaway M, Frierson HF, Hampton G, Theodorescu D. Smith SC, et al. Among authors: theodorescu d. Cancer Res. 2006 Feb 15;66(4):1917-22. doi: 10.1158/0008-5472.CAN-05-3855. Cancer Res. 2006. PMID: 16488989

6

Prediction of drug combination chemosensitivity in human bladder cancer.

Havaleshko DM, Cho H, Conaway M, Owens CR, Hampton G, Lee JK, Theodorescu D. Havaleshko DM, et al. Among authors: theodorescu d. Mol Cancer Ther. 2007 Feb;6(2):578-86. doi: 10.1158/1535-7163.MCT-06-0497. Mol Cancer Ther. 2007. PMID: 17308055

7

Expression profiling of Ral-depleted bladder cancer cells identifies RREB-1 as a novel transcriptional Ral effector.

Oxford G, Smith SC, Hampton G, Theodorescu D. Oxford G, et al. Among authors: theodorescu d. Oncogene. 2007 Nov 1;26(50):7143-52. doi: 10.1038/sj.onc.1210521. Epub 2007 May 14. Oncogene. 2007. PMID: 17496927

8

Depletion of major vault protein increases doxorubicin sensitivity and nuclear accumulation and disrupts its sequestration in lysosomes.

Herlevsen M, Oxford G, Owens CR, Conaway M, Theodorescu D. Herlevsen M, et al. Among authors: theodorescu d. Mol Cancer Ther. 2007 Jun;6(6):1804-13. doi: 10.1158/1535-7163.MCT-06-0372. Mol Cancer Ther. 2007. PMID: 17575109

9

Expression of ral GTPases, their effectors, and activators in human bladder cancer.

Smith SC, Oxford G, Baras AS, Owens C, Havaleshko D, Brautigan DL, Safo MK, Theodorescu D. Smith SC, et al. Among authors: theodorescu d. Clin Cancer Res. 2007 Jul 1;13(13):3803-13. doi: 10.1158/1078-0432.CCR-06-2419. Clin Cancer Res. 2007. PMID: 17606711

10

Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76).

Herlevsen MC, Theodorescu D. Herlevsen MC, et al. Among authors: theodorescu d. Biochem Biophys Res Commun. 2007 Oct 12;362(1):56-62. doi: 10.1016/j.bbrc.2007.07.163. Epub 2007 Aug 8. Biochem Biophys Res Commun. 2007. PMID: 17706599 Free PMC article.

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