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Lmod2 is necessary for effective skeletal muscle contraction.
Larrinaga TM, Farman GP, Mayfield RM, Yuen M, Ahrens-Nicklas RC, Cooper ST, Pappas CT, Gregorio CC. Larrinaga TM, et al. Among authors: farman gp. Sci Adv. 2024 Mar 15;10(11):eadk1890. doi: 10.1126/sciadv.adk1890. Epub 2024 Mar 13. Sci Adv. 2024. PMID: 38478604 Free PMC article.
In vivo elongation of thin filaments results in heart failure.
Mi-Mi L, Farman GP, Mayfield RM, Strom J, Chu M, Pappas CT, Gregorio CC. Mi-Mi L, et al. Among authors: farman gp. PLoS One. 2020 Jan 3;15(1):e0226138. doi: 10.1371/journal.pone.0226138. eCollection 2020. PLoS One. 2020. PMID: 31899774 Free PMC article.
Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy.
Ahrens-Nicklas RC, Pappas CT, Farman GP, Mayfield RM, Larrinaga TM, Medne L, Ritter A, Krantz ID, Murali C, Lin KY, Berger JH, Yum SW, Carreon CK, Gregorio CC. Ahrens-Nicklas RC, et al. Among authors: farman gp. Sci Adv. 2019 Sep 4;5(9):eaax2066. doi: 10.1126/sciadv.aax2066. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31517052 Free PMC article.
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